Results 181 to 190 of about 124,586 (260)

Association between animal welfare indicators and mastitis pathogens in bulk tank milk: the reality of small- and medium-scale dairy cattle farms in Italy. [PDF]

Front Vet Sci
Schleicherová D, Mota-Gutierrez J, Forte C, Ozella L, Fusi F, Vevey M, Bergagna S.   +6 more
europepmc   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

Dietary Supplementation of Olive Pomace in Lactating Buffaloes: Effects on Milk and Yogurt Composition and Fatty Acid Profile. [PDF]

Vet Med Sci
Mohammadabadi T, Amindavar S, Chaji M.
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Advancing the inclusion of pregnant and lactating populations in HIV PrEP research: ethical, regulatory, and surveillance recommendations from a multisectoral working group. [PDF]

Front Public Health
Osakwe CE, Schaefer R, Donaldson L, Abiodun AS, Chatani-Gada M, Chigome AK, Day S, Deaton C, Elemuwa UG, Ingold H, Joseph Davey D, Kersey K, Lamprianou S, Lyerly AD, Noguchi LM, Nyambayo PPM, Mpaso C, Robertson MN, Renaud F, Sehloho T, van Wyk J, Vannappagari V, Warren M, Miller V, Long-Acting PrEP during Pregnancy and Lactation Working Group.   +24 more
europepmc   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

Analysis of differences in gut microbiota structure and function in Bactrian camels under different breeding patterns from northern and southern Xinjiang, China. [PDF]

Front Vet Sci
Yao H, Haire A, Wang Z, Ge T, Liu Y, Hou M, Cui W.   +6 more
europepmc   +1 more source

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

Advanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant, Pouyan Keshavarz Motamed, Thomas Borrillo, Lielle Ronen, Gabriel Siebiger, Guillermo Garza, Hesam Abouali, Md Fahim Al Fattah, Ines Jaber, Dayan Ban, Marcelo Cypel, Mingyao Liu, Shaf Keshavjee, Andrew T. Sage, Mahla Poudineh   +14 more
wiley   +1 more source

Effectiveness of Health Systems Strengthening Implementation Model to Improve Health of Pregnant and Lactating Women by Increasing Compliance with IFA and Calcium Tablets: A Quasi-Experimental Study. [PDF]

Nutrients
Neogi SB, Raushan MR, Kumar S, Babre A, Kathuria N, Mishra A, Kadri AM, Bakshi H, Jani NP, Sidana S, Reddy JC, Hatchard J, Raut M, Kaushik T, Varghese M, Bharai V, Chauhan M, Vala A, Jagtap S, Hallen JB, Choudhary J.   +20 more
europepmc   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source