Results 151 to 160 of about 123,433 (268)

Milk Production Performance, Handling and Utilization Practices, and Compositional Analysis of Local Goats in Garda Marta District, Southern Ethiopia. [PDF]

Vet Med Int
Manta M, Birhanu S, Tadele Y.
europepmc   +1 more source

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

Advanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu, Yaru Sun, Qi Lu, Yi Zhang, Jieruo Li, Huige Hou, Huajun Wang, Hui Tang, Yunsong Zhang, Xiaofei Zheng, Qingsong Mei   +10 more
wiley   +1 more source

Early-Life High-Fat-Diet Exposure Induced Pre-Puberty Obesity-Related MASLD via Autophagy-Mediated Ferroptosis in Male C57BL/6J Mice. [PDF]

Nutrients
Zhang Z, Wu Y, Wu X, Zhao Y, Liang C, Xu J, Nie Z, Liu S, Lv T, Wu M, Zhai L.   +10 more
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Maternal bis-glycinate bound zinc supplementation alters sow performance and milk metabolomic-lipidomic profiles and mitigates piglet diarrhea. [PDF]

Vet Anim Sci
Ruampatana J, Settachaimongkon S, Soodsaward N, Chuaydamrong B, Rukklang P, Boonyasantisuk S, Ratchatakajornkit S, Yamsrikaew U, Homyog K, Kuabphimai R, Vimuktalop L, Suwimonteerabutr J, Nuntapaitoon M.   +12 more
europepmc   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Maternal characteristics associated with ovalbumin concentrations in breast milk. [PDF]

Pediatr Allergy Immunol
Hughes SA, Metcalfe JR, Perrella SL, Geddes DT, Palmer DJ.   +4 more
europepmc   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Nonclinical Considerations for Support of Pregnancy and Lactation in Clinical Trials. [PDF]

Birth Defects Res
Stanislaus D, Bowman CJ, Brannen KC, Campion SN, Carlson LM, Chalon S, DeLise AM, Demarta-Gatsi C, Enright BP, Halpern W, Mitchell-Ryan S, Sutherland V, Thacker K, Thompson K, Tornesi B, Van Cruchten S, Wange RL, White T, Chen CL.   +18 more
europepmc   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source