Results 271 to 280 of about 339,670 (343)

Interfacing mechanistic and breeding scheme simulation to predict selection response on lactation efficiency in dairy cows under different nutritional environments. [PDF]

Genet Sel Evol
Bouquet A, Slagboom M, Thomasen JR, Kargo M, Friggens NC, Puillet L.   +5 more
europepmc   +1 more source

GLUL Confers Perivascular Cancer‐Associated Fibroblasts With Pro‐Angiogenic Capacity to Promote Glioma Progression

Advanced Science, EarlyView.
Schematic illustration of the proposed model. Primary CAFs are isolated from fresh human GBM specimens according to established protocols. GLUL is essential for pro‐angiogenic capacity of CAFs through its impact on the PI3K/AKT pathway. GLUL enhances the pro‐angiogenic capacity of CAFs, driving aberrant tumor vasculature that fuels tumor growth ...
Qing Zhang, Yida Liu, Zhi Zhang, Yang Wang, Fusheng Liu   +4 more
wiley   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Evaluating the efficacy of frenotomy in breastfeeding success: a review of current guidelines and outcomes. [PDF]

Front Pediatr
Sabharwal KA, Simon MW.
europepmc   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

High-fidelity telesimulation to teach lactation skills to primary care residents, a cluster randomized educational trial. [PDF]

BMC Med Educ
Hoyt-Austin A, Sadovnikova A, Muñoz S, Donohue LT, Tancredi DJ, Kair LR.   +5 more
europepmc   +1 more source

Lactate

, 2018
Poblete, Glenn Hernández, Nijsten, Maarten W., Bakker, Jan   +2 more
openaire   +2 more sources

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Longitudinal study of the udder microbiome using genome-centric metagenomics uncovers pathogen-driven adaptation and succession. [PDF]

NPJ Biofilms Microbiomes
Duarte VDS, Franklin FV, Krysmann A, Porcellato D.   +3 more
europepmc   +1 more source

Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data. [PDF]

Front Nutr
Hong F, Song L, Chu X, Zhu Y, Wei Y, Wang J, Zou R, Ji J.   +7 more
europepmc   +1 more source