Results 271 to 280 of about 320,572 (345)

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Correction to: Examining psychosocial pathways to explain the link between breastfeeding practices and child behaviour in a longitudinal cohort

BMC Public Health
Sarah E. Turner, Leslie Roos, Nathan Nickel, Jacqueline Pei, Piushkumar J. Mandhane, Theo J. Moraes, Stuart E. Turvey, Elinor Simons, Padmaja Subbarao, Meghan B. Azad   +9 more
doaj   +1 more source

Safety and Effectiveness of Pain Medications for Migraine Management During Pregnancy and Lactation. [PDF]

Paediatr Drugs
Smirnoff L, Mancera NG, Hyppolite T, Lozano D, Cocores A.   +4 more
europepmc   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Material consequences: an initial assessment of the influence of flooring type on lactating sow thermoregulation in summer heat. [PDF]

Transl Anim Sci
Johnson JS, Rodman A, Sullivan CR, Hopkins C.   +3 more
europepmc   +1 more source

Evaluation of Adaptive, Productive and Reproductive Performance of Boran Dairy Breed in the Lowland Agro-Ecology of Kaffa Zone, South-Western Ethiopia. [PDF]

Vet Med Sci
Nigatu EW.
europepmc   +1 more source

Heat Stress, Indoor Microclimate, and Lactation Feed Intake in Commercial Mediterranean Sows: Parity Effects and a Daily Resolution Predictive Model. [PDF]

Life (Basel)
Fotos L, Pourlis A, Valasi E, Papakonstantinou GI, Kousenidis K, Sougias A, Tsegas G, Chourdakis E, Tsiropoulos Z, Michailidou AV, Vlachocostas C, Papatsiros VG.   +11 more
europepmc   +1 more source

Effects of a cheese co-product fed in lactation and nursery diets on sow, litter, and subsequent nursery pig performance. [PDF]

Transl Anim Sci
Privett GA, Woodworth JC, DeRouchey JM, Gaffield KN, Gebhardt JT, Tokach MD, Goodband RD, Lopez DA.   +7 more
europepmc   +1 more source