Results 161 to 170 of about 122,904 (360)

Clinical Disorders in Holstein Cows: Incidence and Associations among Lactational Risks Factors [PDF]

, 2001
Petr Fleischer, Moritz Metzner, Martina Hoedemaker, Soňa Šlosárková, Miroslav Skřivánek   +4 more
openalex   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Efficient and Specific PDGFRβ‐Targeting Dual‐Mode T1‐T2 MRI Nanoprobe for Early Diagnosis of Non‐Alcoholic Fatty Liver

Advanced Science, EarlyView.
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li, Tongwei Zhang, Tongxiang Tao, Yaxuan Liu, Haining Xia, Sajid ur Rehman, Zeyong Guo, Jing Zhang, Ruiguo Chen, Zhan Zhang, Junfeng Wang, Kun Ma   +11 more
wiley   +1 more source

The genetic relationship of body weight and early-lactation health disorders in two experimental herds [PDF]

, 2010
E. Frigo, C.D. Dechow, O. Pedron, B.G. Cassell   +3 more
openalex   +1 more source

Ultra‐low LOD H2O2 Sensor Based on Synergistic Nernst Potential Effect

Advanced Science, EarlyView.
Due to the synergistic effect of ENernst,H2O2${E}_{\mathrm{Nernst},\ {\mathrm{H}}_{2}{\mathrm{O}}_{2}}$ and ENernst,H+${E}_{\mathrm{Nernst},\ {\mathrm{H}}^{+}}$, the proposed sensors in this study can achieve ultralow H2O2 detection limit as low as 1.8 × 10−12 M based on the stacked PEDOT: BTB/PEDOT: PSS semiconducting layer.
Zhaoqun Wang, Wen Gao, Xiaorong Niu, Yuhang Liu, Zichen Jin, Fan Zhang, Zhengdong Cheng, Xiaoning Jiang, Wendong Zhang, Ting Wang, Jianlong Ji, Xiaojie Chai, Shengbo Sang   +12 more
wiley   +1 more source

Rumination time and monitoring of health disorders during early lactation

Animal, 2018
The objective was to evaluate the association between changes in daily rumination time (dRT) and early stages of disease during early lactation and to assess the performance of two proposed disease detection indices.
S. Paudyal, F.P. Maunsell, J.T. Richeson, C.A. Risco, D.A. Donovan, P.J. Pinedo   +5 more
doaj  

Biochemical profile in dairy cows with artificial induction of lactation

Pesquisa Veterinária Brasileira
: The objective of this study was to determine the biochemical profile of dairy cows with induced lactation. For comparison, another group of normally calved cows was used as control.
Renan B. Paiano, Fábio C. Lahr, Diego A.S. Poit, Artur G.B.V.B. Costa, Daniela B. Birgel, Eduardo H. Birgel Junior   +5 more
doaj   +1 more source

Genetic relationships between claw health traits of dairy cows in different parities, lactation stages, and herds with different claw disorder frequencies [PDF]

, 2015
D. van der Spek, J.A.M. van Arendonk, H. Bovenhuis   +2 more
openalex   +1 more source

DNA methylation changes in the hippocampus of learning and memory disorder offspring rats of lead exposure during pregnant and lactation period [PDF]

, 2020
Tao Hong, Shou-Ming Li, Bo Jia, Yun Huang, Shu Kun, Ke-Wang Yuan, Lai Chen, Long-Xue Li, Li Liu, Zhiyong Liu   +9 more
openalex   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source