Results 161 to 170 of about 3,019,565 (364)

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Biochemical profile in dairy cows with artificial induction of lactation

Pesquisa Veterinária Brasileira
: The objective of this study was to determine the biochemical profile of dairy cows with induced lactation. For comparison, another group of normally calved cows was used as control.
Renan B. Paiano, Fábio C. Lahr, Diego A.S. Poit, Artur G.B.V.B. Costa, Daniela B. Birgel, Eduardo H. Birgel Junior   +5 more
doaj   +1 more source

The genetic relationship of body weight and early-lactation health disorders in two experimental herds [PDF]

, 2010
E. Frigo, C.D. Dechow, O. Pedron, B.G. Cassell   +3 more
openalex   +1 more source

DNA methylation changes in the hippocampus of learning and memory disorder offspring rats of lead exposure during pregnant and lactation period [PDF]

, 2020
Tao Hong, Shou-Ming Li, Bo Jia, Yun Huang, Shu Kun, Ke-Wang Yuan, Lai Chen, Long-Xue Li, Li Liu, Zhiyong Liu   +9 more
openalex   +1 more source

Prevalence of iron deficiency in 62,685 women of seven race/ethnicity groups: The HEIRS Study. [PDF]

, 2020
BackgroundFew cross-sectional studies report iron deficiency (ID) prevalence in women of different race/ethnicity and ages in US or Canada.Materials and methodsWe evaluated screening observations on women who participated between 2001-2003 in a cross ...
Acton, Ronald T, Adams, Paul C, Barton, James C, Eckfeldt, John H, Gordeuk, Victor R, Harris, Emily L, Harrison, Helen, McLaren, Christine E, McLaren, Gordon D, Reboussin, David M, Wiener, Howard H   +10 more
core  

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Genetic relationships between claw health traits of dairy cows in different parities, lactation stages, and herds with different claw disorder frequencies [PDF]

, 2015
D. van der Spek, J.A.M. van Arendonk, H. Bovenhuis   +2 more
openalex   +1 more source

PFKM‐Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation

Advanced Science, EarlyView.
The upregulation of PFKM activates glycolysis, thereby enhancing lactate production in atrial tissue. Atrial lactate accumulation promotes global lactylation and H3K18 lactylation in atrial fibroblasts. P300‐mediated H3K18 lactylation up‐regulates TGF‐β1 transcription, leading to fibroblast activation and thereby contributing to atrial fibrosis.
Ning Fang, Ning Zhang, Xiaohui Jiang, Sen Yan, Zhiqi Wang, Qianhui Gao, Mingcheng Xu, Lin Mu, Xiaoming Li, Jiuling Chen, Song Zhang, Yu Duan, Fengxiang Yun, Luyifei Li, Yun Zhang, Yongtai Gong   +15 more
wiley   +1 more source

Rumination time and monitoring of health disorders during early lactation

Animal, 2018
The objective was to evaluate the association between changes in daily rumination time (dRT) and early stages of disease during early lactation and to assess the performance of two proposed disease detection indices.
S. Paudyal, F.P. Maunsell, J.T. Richeson, C.A. Risco, D.A. Donovan, P.J. Pinedo   +5 more
doaj  

Genetic parameters of growth in dairy cattle and associations between growth and health traits [PDF]

, 2007
Abdallah, Berry, Brotherstone, Coffey, Coffey, Coffey, Coffey, G. Banos, Groen, Hansen, Hoffman, Kirkpatrick, Koenen, M.P. Coffey, Miglior, Mourits, Mäntysaari, Pryce, Rauw, S. Brotherstone, Tsuruta, van Elzakker, Veerkamp, Veerkamp, Veerkamp, Visscher, Wall   +26 more
core   +1 more source