Results 291 to 300 of about 122,904 (360)

Molecular Fragmentation as a Strategy to Access Hyperpolarized Compounds from Para‐Hydrogen

ChemPhysChem, EarlyView.
Hyperpolarization using para‐hydrogen is a simple and cost‐effective method to dramatically increase sensitivity in magnetic resonance. When combined with chemical reactions that generate smaller fragments, a much wider array of different hyperpolarized molecules can be accessed.
Philip L. Norcott
wiley   +1 more source

Advancing inclusive healthcare through PBPK modelling: predicting the impact of CYP genotypes and enzyme ontogenies on infant exposures of venlafaxine and its active metabolite O-desmethylvenlafaxine in lactation. [PDF]

J Pharmacokinet Pharmacodyn
Pan X, Rowland Yeo K.
europepmc   +1 more source

Optimizing Patient Registries for Regulatory Decision Making ‐ Key Learnings From an HMA/EMA Multistakeholder Workshop

Clinical Pharmacology &Therapeutics, EarlyView.
The Joint Heads of Medicines Agencies and European Medicines Agency's (HMA/EMA) big data initiative paves the way for better integration of real‐world data, including data from patient registries, into regulatory decisions on medicines. This article focuses on the outcome of a two‐day multistakeholder workshop organized by EMA in 2024, which explored ...
Kelly Plueschke, Carla Jonker, Hanna Kankanen, Thorsten Vetter, Bruno Sepodes, Lutz Naehrlich, Jan Hillert, Gracy Crane, Sabine Straus, Paolo Foggi, Simona Martin, Christina Kyriakopoulou, Peter Mol, Francesca Day, Kieran Breen, Neil Bennett, Mencia de Lemus Belmonte, Simon Bennett, Patrice Verpillat, Kit C. B. Roes, Ana Cochino, Franz Schaefer, Jesús María Hernández‐Rivas, Patricia McGettigan, Peter Arlett   +24 more
wiley   +1 more source

Twinning in Italian Holstein Cows: A Retrospective Study on Risk Factors and Its Associations with Milk Production, Fertility, and Survival. [PDF]

Vet Sci
Guadagnini M, Amodeo P, Bolli A, Probo M.   +3 more
europepmc   +1 more source

Mechanisms of Change in Cognitive‐Behavioral Therapy for Adults With Binge‐Eating Disorder: A Dynamic Structural Equation Modeling Approach

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Cognitive‐behavioral therapy (CBT) is the most well‐established treatment for binge‐eating disorder (BED), but the mechanisms of change remain poorly understood. This study investigated in CBT for BED the effects of overvaluation of shape and weight and dietary restraint on subsequent objective binge‐eating episodes (OBEs). Method In
Ricarda Schmidt, Danielle Schewe, Stephan Herpertz, Stephan Zipfel, Brunna Tuschen‐Caffier, Hans‐Christoph Friederich, Andreas Mayr, Martina de Zwaan, Anja Hilbert   +8 more
wiley   +1 more source

Good practice in lactation counseling for Ukrainian refugee mothers to ensure the health and mental benefits of breastfeeding - an observational study. [PDF]

Arch Womens Ment Health
Babiszewska-Aksamit M, Bzikowska-Jura A, Kotlińska A, Aduła A, Chrobak A, Domosud J, Drążkowska I, Gaweł P, Jakimiuk A, Kołodziej J, Królak-Olejnik B, Lisak-Gurba K, Mozdyniewicz K, Mołas A, Piątkowska A, Sinkiewicz-Darol E, Wesołowska A.   +16 more
europepmc   +1 more source

Smartphone‐Supported Cognitive‐Behavioral Therapy in Binge‐Eating Disorder: An Exploratory Randomized Trial

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To assess the feasibility of a smartphone app delivering just‐in‐time adaptive interventions as an adjunct to cognitive‐behavioral therapy (CBT) adapted to binge‐eating disorder (BED), estimate its effects assuming superiority over CBT alone, and document safety and target engagement.
Anja Hilbert, Ulrike Klotz, Sina Sadeghi, Adrienne S. Juarascio, Toralf Kirsten   +4 more
wiley   +1 more source

A qualitative inquiry of speech-language therapists' views about breastfeeding management. [PDF]

S Afr J Commun Disord
Schlome D, Krüger E, Pillay B.
europepmc   +1 more source

Multicentre comparison of various microaxial pump devices as a bridge to durable assist device implantation

ESC Heart Failure, EarlyView.
In the context of patients with severe heart failure, it is crucial to ensure adequate preconditioning before considering the implantation of dLVAD. Although several types of mechanical circulatory assist devices are available and all offer a significant advantage, the present study suggests that the higher the flow rate provided by the Impella®, the ...
Marta L. Medina, Daniel Lewin, Hendrik Treede, Sebastian V. Rojas, Alexander Bernhardt, Michael Billion, Anna L. Meyer, Ivan Netuka, Janajade Kooij, Marina Pieri, Antonio Loforte, Mauro Rinaldi, Mariusz K. Szymanski, Adriaan O. Kraajieveld, Christian J.H. Moeller, Payam Akhyari, Khalil Jawad, Bastian Schmack, Gloria Färber, Assad Haneya, Daniel Zimpfer, Gaik Nersesian, Ilija Djordjevic, Diyar Saeed, Finn Gustafsson, Anna M. Scandroglio, Bart Meyns, Steffen Hofmann, Jan Belohlavek, Jan Gummert, Pia Lanmueller, Evgenij V. Potapov, Mehmet Oezkur   +32 more
wiley   +1 more source

Efficacy of red ointment in wound cavity repair following non-puerperal mastitis debridement. [PDF]

Hereditas
Feng J, Chen Z, Sun J, Shao S, Xie L, Qu W, Gao Q, Wu X, Wan H.   +8 more
europepmc   +1 more source