Results 291 to 300 of about 5,526,205 (386)

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

Cell Metabolism, 2016
Almut Brand, K. Singer, G. Koehl, M. Kolitzus, Gabriele Schoenhammer, A. Thiel, Carina Matos, Christina Bruss, S. Klobuch, K. Peter, M. Kastenberger, C. Bogdan, U. Schleicher, A. Mackensen, E. Ullrich, S. Fichtner-Feigl, R. Kesselring, M. Mack, U. Ritter, M. Schmid, C. Blank, K. Dettmer, P. Oefner, P. Hoffmann, S. Walenta, E. Geissler, J. Pouysségur, A. Villunger, A. Steven, B. Seliger, S. Schreml, S. Haferkamp, E. Kohl, S. Karrer, M. Berneburg, W. Herr, W. Mueller‐Klieser, K. Renner, M. Kreutz   +38 more
semanticscholar   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Highly efficient degradation of lactic acid by microwave-induced activated carbon catalytic oxidation process. [PDF]

iScience
Liang F, Liu Y, Yang S, Wang Y, Peng Y.
europepmc   +1 more source

THE UTILIZATION OF PEPTIDES BY LACTIC ACID BACTERIA

, 1948
Willard A. Krehl, Joseph S. Fruton
openalex   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Isolation, identification, and evaluation of the antioxidant properties of lactic acid bacteria strains isolated from meat environment. [PDF]

PLoS One
Łepecka A, Szymański P, Okoń A.
europepmc   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

Lactic acid inhibits melanin synthesis by regulating histone H3 lactylation and suppressing tyrp1 transcription in B16 melanoma cells. [PDF]

Sci Rep
Du B, Xiao M, Gao L.
europepmc   +1 more source

FORMATION OF LACTIC ACID, AN INITIAL PROCESS IN WORKING MUSCLE

, 1939
Eunice V. Flock, Dwight J. Ingle, Jesse L. Bollman   +2 more
openalex   +1 more source

Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis

Advanced Science, EarlyView.
Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni, Yufei Cui, Mojtaba Salehi, Mui Ling Sharon Nai, Kun Zhou, Cian Vyas, Boyang Huang, Paulo Bartolo   +7 more
wiley   +1 more source