Results 121 to 130 of about 549,247 (252)

Lag-phase of PruAA5_2A activity.

, 2019
The lag-phase (tlag) is defined as the time from initiation of the reaction (T = 00:00) to where the maximum slope crosses the x-axis. (A) Impact of buffer type and concentration on rate of product formation during oxidation of 300 mM raffinose (pH 7.5).
Ville Aumala (6703958), Yann Mathieu (487812), Emma Master (669609), Kirsti Parikka (2055325), Maija Tenkanen (684935), Filip Mollerup (6703955), Harry Brumer (811100)   +6 more
core   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Increasing communicative mand topographies : an evaluation of the use of a lag reinforcement schedule embedded in a functional communication training treatment package [PDF]

, 2013
textInvariant responding among individuals with autism spectrum disorder (ASD) is problematic and can be pervasive across all areas of development. Individuals with ASD demonstrate difficulty communicating wants and needs and often engage in challenging
Gainey, Summer
core  

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

The Power of WIL: Advancing Work-Integrated Learning in Discipline-Based Higher Education Programs

Nordic Journal of STEM Education
Profession-oriented and discipline-based higher education programs differ significantly in implementing work-integrated learning (WIL). Discipline-based programs in fields like mathematics, biological and social sciences have only recently begun to ...
Monica Alterskjær Sundset, Ragnhild Sandvoll, Torstein Låg   +2 more
doaj   +1 more source

Performance characteristics of the CDC-modified Bio-Rad-Avidity (AI: 30%) and the Sedia-LAg-Avidity (ODn: 1.5) assays.

, 2016
Performance characteristics of the CDC-modified Bio-Rad-Avidity (AI: 30%) and the Sedia-LAg-Avidity (ODn: 1.5) assays.
Denis Hamel (2806267), Florence Doualla-Bell (641160), Cécile Tremblay (141827), Mario Legault (2806276), Micheline Fauvel (2806273), Bouchra Serhir (2806270), Jean Pierre Routy (588538), Sylvie-Nancy Beaulac (2806279)   +7 more
core   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source