Results 201 to 210 of about 1,649,596 (282)

Dermal Alpha-Synuclein Aggregation in Seed Amplification Assays for Parkinson's Disease Subtype Differentiation. [PDF]

open access: yesEur J Neurol
Vieregge M   +6 more
europepmc   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang   +9 more
wiley   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras   +19 more
wiley   +1 more source

Expression of the inhibitory checkpoints LAG-3, TIM-3, and PD-1 in NK cells and T cells in acute myeloid leukemia: preserved expression of LAG-3 is associated with patient survival. [PDF]

open access: yesCancer Immunol Immunother
Valhondo I   +14 more
europepmc   +1 more source

Sonication‐Assisted Palladium Nanogaps in a Capacitive Structure: A Tunable and Reliable Solution for Sensitive Hydrogen Monitoring

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a capacitive hydrogen sensor with a simple structure and process. Sonication‐induced Pd nanogaps modulate the effective electrode area in response to hydrogen concentration, resulting in capacitance changes within a range predefined by physical parameters.
Sang‐kil Lee   +9 more
wiley   +1 more source

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