Results 61 to 70 of about 1,649,596 (282)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
PhD on Track og åpen publisering
Nordic Journal of Information Literacy in Higher Education, 2020 PhD on Track er en åpen, fritt tilgjengelig nettressurs beregnet på stipendiater og yngre forskere. I de to siste årene (2017-2018) er ressursen endret fra et dansk-norsk samarbeid til et samarbeid mellom flere norske institusjoner.
Hege Charlotte Faber, Torstein Låg
doaj +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Business Strategy and Audit Efforts - Focusing on Audit Report Lags: An Empirical Study in Korea [PDF]
, 2021 Jihwan Choi, Hyung Ju Park
openalex +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
French birds lag behind climate warming [PDF]
, 2007 Biodiversity responses to climate warming have been documented through the study of changes in distributions, abundances or phenologies of individual species or in more integrated measures such as species community richness and composition.
Denis Couvet +3 more
core +1 more source
Delay time modulation induced oscillating synchronization and intermittent anticipatory/lag and complete synchronizations in time-delay nonlinear dynamical systems [PDF]
, 2007 Existence of a new type of oscillating synchronization that oscillates between three different types of synchronizations (anticipatory, complete and lag synchronizations) is identified in unidirectionally coupled nonlinear time-delay systems having two ...
Lakshmanan, M., Senthilkumar, D. V.
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Zero-lag long-range synchronization of Hodgkin-Huxley neurons is enhanced by dynamical relaying : poster presentation [PDF]
, 2007 Background The synchrony hypothesis postulates that precise temporal synchronization of different pools of neurons conveys information that is not contained in their firing rates.
Fischer, Ingo +3 more
core +1 more source