Results 61 to 70 of about 1,587,709 (329)
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Triple Massey products over global fields [PDF]
, 2015 Let $K$ be a global field which contains a primitive $p$-th root of unity, where $p$ is a prime number. M. J. Hopkins and K. G. Wickelgren showed that for $p=2$, any triple Massey product over $K$ with respect to $\mathbb{F}_p$, contains 0 whenever it is
Minac, Jan, Tan, Nguyen Duy
core
Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep [PDF]
, 2018 Additional file 6: Decreased lag-2 function does not slow vulval development. The progeny of wild type and lag-2(q420) animals raised at 25.5 °C were selected at the L4 stage, prior to lethargus entry. Vulval eversion was scored after 3 h; the percentage
Bennett, Heather L +7 more
core +4 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
On infinite dimensional algebraic transformation groups [PDF]
, 2014 We explore orbits, rational invariant functions, and quotients of the natural actions of connected, not necessarily finite dimensional subgroups of the automorphism groups of irreducible algebraic varieties.
Popov, Vladimir L.
core +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Child L2 development: a longitudinal case study on voice onset times in word-initial stops [PDF]
, 2010 This paper reports the results of a longitudinal case study examining the acquisition of the English voice system by a three-year-old native speaker of Dutch.
Simon, Ellen
core +2 more sources
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Phase Lag and Coherence Function of X-ray emission from Black Hole Candidate XTE J1550-564 [PDF]
, 2000 We report the results from measuring the phase lag and coherence function of X-ray emission from black hole candidate (BHC) XTE J1550-564. These X-ray temporal properties have been recognized to be increasingly important in providing important ...
Kato S. +3 more
core +2 more sources
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source