Results 91 to 100 of about 18,294,799 (361)
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
We report a comprehensive study on spectral and timing properties of hard X-ray dips uniquely observed in some so-called variability classes of the micro-quasars GRS 1915+105 and IGR J17091-3624.
Bhattacharyya, Sudip+5 more
core +2 more sources
The changing X-ray time lag in MCG-6-30-15 [PDF]
MCG-6-30-15 is one of the most observed Narrow Line Seyfert 1 galaxies in the X-ray band. In this paper we examine the X-ray time lags in this source using a total of 600 ks in observations (440 ks exposure) taken with the XMM-Newton telescope (300 ks in
Alston, W.+8 more
core +1 more source
Lag time determination in DEC measurements with PTR-MS [PDF]
The disjunct eddy covariance (DEC) method has emerged as a popular technique for micrometeorological flux measurements of volatile organic compounds (VOCs).
R. Taipale, T. M. Ruuskanen, J. Rinne
doaj +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Premenopausal women and postmenopausal women given estrogen are protected from cardiovascular diseases compared with men. Previous studies investigated whether estrogen treatment protects low density lipoprotein (LDL) from in vitro oxidation as a ...
Dawn C. Schwenke+2 more
doaj
Nitrogen (N) legacy effects are widely recognized as a primary obstacle to the improvements of water quality following mitigation efforts. The exploration of long-term nutrient trajectories for nitrogen model (ELEMeNT-N) has been applied to estimate ...
Jia Zhou+10 more
doaj +1 more source
Time lag and communication in changing unpopular norms. [PDF]
Humans often coordinate their social lives through norms. When a large majority of people are dissatisfied with an existing norm, it seems obvious that they will change it. Often, however, this does not occur.
Klarita Gërxhani, Jeroen Bruggeman
doaj +1 more source
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim+11 more
wiley +1 more source
Reverberation Measurements of the Inner Radius of the Dust Torus in Nearby Seyfert 1 Galaxies
The most intense monitoring observations yet made in the optical (UBV) and near-infrared (JHK) wave bands were carried out for nearby Seyfert1 galaxies of NGC 5548, NGC 4051, NGC 3227, and NGC 7469.
Antonucci R.+16 more
core +2 more sources