Results 91 to 100 of about 1,263,681 (273)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

An audit of studies registered retrospectively with the Clinical Trials Registry of India: A one year analysis

open access: yesPerspectives in Clinical Research, 2019
Background: The Clinical Trials Registry of India (CTRI) was launched in July 2007 and will enter its tenth year in 2017. While its mission is to encourage prospective trial registration, CTRI does permit retrospective trial registration.
Amit R Birajdar   +5 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Study on Attribution Analysis and Response of Saltwater Intrusion in Modaomen Waterway During Dry Seasons

open access: yesRenmin Zhujiang, 2023
Under the influence of climate change and human activities, the saltwater intrusion in the Modaomen Estuary Waterway has intensified significantly,which has greatly threatened the safety of the water supply in the Guangdong-Hong Kong-Macao Greater Bay ...
HUANG Chunhua   +4 more
doaj  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Identification of appropriate temporal scales of dominant low flow indicators in the Main River, Germany [PDF]

open access: yes, 2010
Models incorporating the appropriate temporal scales of dominant indicators for low flows are assumed to perform better than models with arbitrary selected temporal scales.
Booij, Martijn J., Demirel, Mehmet C.
core   +1 more source

Flocking estimates for the Cucker-Smale model with time lag and hierarchical leadership

open access: yes, 2018
We analyze the Cucker-Smale model under hierarchical leadership in presence of a time delay. By using a Lyapunov functional approach and some induction arguments we will prove convergence to consensus for every positive delay $\tau$.
Pignotti, Cristina, Vallejo, Irene Reche
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Microbially‐Mediated Soil Carbon‐Nitrogen Dynamics in Response to Future Soil Moisture Change

open access: yesEarth's Future
The interactions between soil carbon and nitrogen (C‐N) processes with environmental factors, particularly soil moisture, are critical to maintaining soil ecosystem functions.
Wanyu Li   +5 more
doaj   +1 more source

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