Results 91 to 100 of about 176,683 (244)

Real-time actuation of a dielectric elastomer actuator neuroprosthesis for facial paralysis

open access: yesSmart Materials in Medicine
Facial paralysis is a highly burdening condition, resulting in a patient's inability to move his mimic musculature on one or both sides of his face. This condition compromises the patient's communication and facial expressions, and thus dramatically ...
Stefania Konstantinidi   +7 more
doaj   +1 more source

Osteology of the pectoral girdle and forelimb of Siriusgnathus niemeyerorum, a Late Triassic traversodontid cynodont from Brazil

open access: yesThe Anatomical Record, EarlyView.
Abstract Traversodontids are non‐mammaliaform cynodonts, herbivorous to omnivorous, that lived during the Triassic. In the Late Triassic, some members of this group increased in body size relative to other cynodont lineages and evolved postcranial adaptations associated with locomotion.
Jhonata H. A. Martins, Leonardo Kerber
wiley   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

open access: yesArthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat   +14 more
wiley   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease   +20 more
wiley   +1 more source

Type I interferon drives dysfunction of a distinct CD8+ HLA‐DRB1+ T cell subset in systemic lupus erythematosus

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long   +3 more
wiley   +1 more source

Đặc điểm sinh trưởng và các hệ số tử vong của loài tôm sắt choán Parapenaeopsis maxillipedo Alcock, 1905 ở vùng biển Kiên Giang

open access: yesTạp chí Khoa học Đại học Cần Thơ
Đặc điểm sinh trưởng, các hệ số tử vong và hệ số khai thác của loài tôm sắt choán Parapenaeopsis maxillipedo Alcock, 1905 ở vùng biển Kiên Giang được phân tích từ dữ liệu sinh học được thu thập trong khoảng thời gian từ tháng 11/2022 đến tháng 10/2023 ...
Vũ Việt Hà, Từ Hoàng Nhân
doaj  

Personalized Lifespan Approach to Autism Assessment: A Clinical and System Framework for Developmentally Informed Assessment Across the Life‐Course

open access: yesAutism Research, EarlyView.
ABSTRACT The increasing prevalence of autism has led to considerable system challenges as specialist‐driven approaches have struggled to keep pace. Recent research has challenged status quo models by demonstrating that community‐based pediatric clinicians can accurately diagnose autism in young children. This research provides an opportunity to further
Melanie Penner, Rebecca McNally Keehn
wiley   +1 more source

The Unique Roles of Executive Function in Co‐Occurring Psychopathologies in Autism

open access: yesAutism Research, EarlyView.
ABSTRACT Children with autism spectrum disorder (ASD) often experience co‐occurring psychiatric conditions, such as anxiety and attention‐deficit/hyperactivity disorder (ADHD), which significantly impair daily functioning. However, the underlying mechanisms linking these conditions to core ASD features remain poorly understood.
Shing‐Him Ng   +13 more
wiley   +1 more source

Short Report: An Examination of Children's Autism Traits and Their Association With Family Experience

open access: yesAutism Research, EarlyView.
ABSTRACT The present study examined how the frequency and impact of autism traits were associated with parent‐reported family experience, with differential consideration of parental experience and overall family life. Prior research has found an association between autism traits and family functioning; however, less is known about how the impact and ...
Ella C. Brouwer   +28 more
wiley   +1 more source

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