Results 121 to 130 of about 2,378 (250)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

The Political Economy of Immigrants Naturalization [PDF]

open access: yes
This paper provides the first political economy model in which self-interested natives decide when voting rights should be granted to foreign-born workers. This choice is driven by the maximization of th net gains from immigration.
Fabio, MARIANI
core  

Relations of Turkey with the European Union a candidate forever? [PDF]

open access: yes, 2008
This paper primarily addresses three aspects of Turkish-EU relations: the first section of the study gives an overview of the history of Turkey’s relations with and the EEC/EC/ EU in the period between 1959 and 2008, focusing on “the Ankara Agreement” of
Yılmaz, Bahri, Yilmaz, Bahri
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Política y secularización en la Europa contemporánea

open access: yesStudia Historica: Historia Contemporánea, 2010
RESUMEN: Este trabajo se ocupa de la relación entre la política y los procesos de secularización en la Europa contemporánea, estudia sus variantes y opciones ideológicas, así como sus diferentes tradiciones y situaciones nacionales, poniendo de relieve ...
Manuel ÁLVAREZ TARDÍO
doaj  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Governance Systems in the Management of Multireligious Societies: The Spanish Model

open access: yesReligions
This article addresses the need to rethink models for managing religious diversity in Europe, which, among other causes, has transformed into a multi-religious society, breaking with Christian hegemony as a result of the migration processes of the last ...
Jaime Rossell
doaj   +1 more source

WHAT STORIES DOES EUROPE TELL? A VIEW FROM TURKEY. CES Open Forum Series 2018-2019 CES Open Forum Series 2018-2019 [PDF]

open access: yes, 2019
Turkey’s omnipresence at the margins of Europe throughout history has given shape to both Turkish and European identities. This paper sheds light onto this relationship by endeavoring to go beyond the much studied institutional relationship between ...
Kadıoğlu, Ayşe
core  

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

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