Results 141 to 150 of about 2,378 (250)

Debating the 'integration of Islam': the discourse between governmental actors and Islamic representatives in Germany and the Netherlands. [PDF]

Comp Migr Stud, 2018
Kortmann M.
europepmc   +1 more source

Gaos, intérprete de la modernidad como totalitarismo / Gaos interpreter of the crisis of Modernity as Totalitarianism

Bajo Palabra, 2017
Este artículo investiga, especialmente en los materiales inéditos del archivo de Gaos, la noción de totalitarismo como diagnóstico de su época. Gaos considera que a la modernización como proceso de laicización, tecnificación y degradación del sujeto y ...
Sergio Sevilla Segura
doaj  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Imágenes especulares: Educación, laicidad y catolicismo en Santa Fe, 1900-1940

Prohistoria, 2009
El presente trabajo se interroga en torno a las relaciones entre catolicismo y laicismo en el terreno educativo. Se pregunta, en particular, sobre la consistencia historiográfica de las imágenes construidas como reflejo de la tesis del "renacimiento ...
Diego A. Mauro
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Changing direction: the struggle of regulating assisted reproductive technology in Austria. [PDF]

Reprod Biomed Soc Online, 2016
Griessler E, Hager M.
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

LAICIDAD DEL ESTADO Y ORDENAMIENTO JURÍDICO: LIBERTAD VS. UNIFORMIDAD: EL CASO ESPAÑOL Laicism (laity) of the State and legal system: Freedom vs. uniformity: The Spanish case

Ius et Praxis, 2010
Nos planteamos en este estudio el problema de la cohonestación (coordinación) dentro de los ordenamientos democráticos de la laicidad del Estado con la libertad religiosa de sus ciudadanos.
Arturo Calvo Espiga
doaj