Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Comparative anthropology of Buddhism workshop: the laity
, 2015 Organized as a collaboration between the Centre for Himalayan Studies and the Southeast Asia Centre units of the French CNRS, a series of day-long thematic workshops in the comparative anthropology of Buddhism is held in Paris over a period of two years (
Nicolas Sihlé
core
The Problem of Trust Without Intimacy: Education for Handling Expert Knowledge in a Neoliberal Marketplace. [PDF]
Sci Educ (Dordr), 2022 Smith DV.
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
The Role of the Laity in the Thought of John Ireland
, 1990 John Ireland had an evolving vision of the Catholic laity\u27s mission in the United States. Archbishop Ireland of St. Paul, Minnesota, was an influential member of the United States hierarchy in the late nineteenth and early twentieth centuries.
McLaughlin, Katherine A.
core
St Andrews Encyclopaedia of TheologyThe Canon Law of the Roman Catholic Church is contained in two Codes that legislate on the way the Church is organized and carries out its activities in the world.
Patrick Valdrini
doaj
Educating future scientists towards post-patrimonial governance. [PDF]
Cult Stud Sci Educ, 2021 Smith DV.
europepmc +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
In Situ Identification of Secondary Structures in Unpurified Bombyx mori Silk Fibrils Using Polarized Two-Dimensional Infrared Spectroscopy. [PDF]
Biomacromolecules, 2022 Giubertoni G +7 more
europepmc +1 more source