Results 11 to 20 of about 589 (104)

Elevated Serum Bile Acids Predict Poor Liver Outcomes in Children With Alagille Syndrome: Results From the GALA Study Group. [PDF]

Liver Int
ABSTRACT Background and Aim Alagille syndrome (ALGS) is a rare disorder characterised by cholestasis and extrahepatic manifestations. Given the current era of ileal bile acid transporter (IBAT) inhibitor therapies that reduce serum bile acid (SBA) levels, we evaluated whether SBA predicts liver disease outcomes in ALGS.
Perez CFM, Vandriel SM, Gonzales EM, Wang JS, Li LT, She H, Jankowska I, Czubkowski P, Gliwicz-Miedzińska D, Jacquemin E, Bouligand J, D'Antiga L, Nicastro E, Fischler B, Arnell H, Siew SM, Stormon M, Loomes KM, Piccoli DA, Rand EB, Squires JE, Karpen SJ, Romero R, Kasahara M, Önal Z, Sokal É, Demaret T, Wiecek S, Lacaille F, Debray D, Hardikar W, Shankar S, Valentino PL, Sundaram SS, Ebel NH, Feinstein JA, Waisbourd-Zinman O, Lin HC, Rock N, Verkade HJ, Jensen MK, Jaramillo C, Kim KM, Oh SH, Brecemiclj J, Alam S, Indolfi G, Blondet N, Fawaz R, Nastasio S, Calvo PL, Nebbia G, Arikan C, Larson-Nath C, Zizzo AN, Sandahl TD, Tzivinikos C, El-Koofy NM, Elmonem MA, Aqul AA, Karnsakul W, Bulut P, Kerkar N, Wolters VM, Roberts AJ, Evans HM, Sanchez MC, Cavalieri ML, Kelly DA, Hartley J, Lee WS, Hajinicolaou C, Lertudomphonwanit C, Fischer RT, Bernabeu JQ, Quiros-Tejeira RE, Ferreira CT, Carvalho E, Eshun J, Zellos A, Dezsőfi A, Pinto RB, Schwarz K, Rogalidou M, Garcia J, Tamara ML, Beretta M, Mujawar Q, Santos-Silva E, Busoms CM, Lurz E, Gonçalves C, Jimenez-Rivera C, Banales JM, Thompson RJ, Hansen BE, Kamath BM, Global ALagille Alliance (GALA) Study Group.   +97 more
europepmc   +2 more sources

Phenotypic Divergence of JAG1- and NOTCH2-Associated Alagille Syndrome & Disease-Specific NOTCH2 Variant Classification Guidelines. [PDF]

Liver Int
ABSTRACT Background & Aims Alagille syndrome (ALGS) is a rare, autosomal dominant disorder with high phenotypic heterogeneity. Disease‐causing variants are primarily identified in Jagged1 (JAG1), with fewer reported in NOTCH2. JAG1 variants cause disease through a mechanism of haploinsufficiency, but the mechanism for NOTCH2 variants is not completely ...
Vandriel SM, Li LT, She H, Wang JS, Loomes KM, Piccoli DA, Jankowska I, Czubkowski P, Gliwicz-Miedzińska D, D'Antiga L, Nicastro E, Lacaille F, Debray D, Sokal ÉM, Demaret T, Fawaz RL, Nastasio S, Kim KM, Oh SH, Fischler B, Arnell H, Larson-Nath C, Hardikar W, Shankar S, Sundaram SS, Chaidez A, Bulut P, Calvo PL, Kasahara M, Blondet N, Lurz E, Kavallar AM, Gonzales EM, Jacquemin E, Bouligand J, Ebel NH, Feinstein JA, Siew SM, Stormon MO, Karpen SJ, Romero R, Jensen MK, Jaramillo C, Squires JE, Bedoyan SM, Kelly DA, Hartley J, Verkade HJ, Lee WS, Lertudomphonwanit C, Fischer RT, Lin HC, Rock N, Mozer-Glassberg Y, Roberts AJ, Evans HM, Karnsakul W, Nebbia G, Wolters VM, Valentino PL, Bernabeu JQ, Aqul AA, Arikan C, Tamara ML, Busoms CM, Sandahl TD, Indolfi G, Zizzo AN, Zellos A, Quiros-Tejeira RE, Santos-Silva E, Schwarz KB, Brecelj J, Sanchez MC, Cavalieri ML, Tzivinikos C, Wiecek S, Eshun J, Kerkar N, Mujawar Q, Önal Z, Gonçalves C, Garcia J, Alam S, Jimenez-Rivera C, Bujanda L, Thompson RJ, Hansen BE, Spinner NB, Gilbert MA, Kamath BM, Global ALagille Alliance (GALA) Study Group.   +91 more
europepmc   +2 more sources

Thank You to Our 2025 Peer Reviewers [PDF]

Geohealth
GeoHealth, Volume 10, Issue 4, April 2026.
Nguyen T, Anyamba A, Balbus J, Chen K, Dey S, Franklin M, Fu T, Gao M, Jiang S, Liu Y, Paytan A, Usmani M, Yim S.   +12 more
europepmc   +2 more sources

Ecological, Molecular, Histopathological and Public Health Implications of Zoonotic Metacercariae Clinostomum complanatum (Rudolphi, 1814) in the Endemic Anatolian Fish, Alburnus escherichii. [PDF]

Vet Med Sci
• Clinostomum complanatum metacercariae, which has been reported in 23 fish species worldwide and 12 in Türkiye to date, continues to infect local and endemic fish species and will persist in the future. • Considering that Alburnus escherichii and other fish species in which this parasite has been recorded in Türkiye are used in traditional local ...
Aydogdu N, Mattiucci S, Palomba M, Aydogdu A, Ürkü Ç, Yılmaz HE, Çağatay IT, Aksu S.   +7 more
europepmc   +2 more sources

Anthropogenically-Induced Ecological Risks in Lake Gala, Thrace, NW Turkey

International Journal of Environment and Geoinformatics, 2023
The aim of this study is to determine the anthropogenic effects in lake Gala in the Thrace Region and to make an ecological risk analysis as a result of these effects. Based on the multi-element analyzes of the samples collected from the lake by Grab and Core method, using ICP-MS, which is frequently used in the calculation of ecological risk in ...
openaire   +2 more sources

An Untapped and Undocumented Butterfly Diversity in a Rapidly Urbanizing and Fragmenting Forest Habitat in Pokhara, Nepal: First Checklist and Implications for Conservation and Ecotourism. [PDF]

Ecol Evol
Documenting indicator taxa such as butterflies is crucial in biodiversity hotspots such as the Himalayas, particularly in rapidly urbanizing areas such as Pokhara, Nepal. This study recorded 225 butterfly species in the Methlang Forest area of Lakeside, Pokhara, including new and long‐absent national records.
Kc S.
europepmc   +2 more sources

Geophysical prospections support the historical identification of the archaeological site at Lake Gala, Hebros/Maritsa/Meriç delta (Turkey)

, 2023
Archaeological survey and combined geophysical measurements of magnetics were conducted. Geoelectrics and ground penetrating radar support the interpretation of a Roman station controlling a branch of the Via Egnatia leading to Ainos (modern Enez in Turkey).
Dan, Anca, Erkul, Ercan, Fischer, Simon, Stümpel, Harald, Bașaran, Sait, Çokaman, Elif, Lapierre, Luc, Brückner, Helmut, Rabbel, Wolfgang   +8 more
openaire   +1 more source

Essential and toxic element bioaccumulations in fishes of gala and siğirci lakes (Meriç River Delta, Turkey) [PDF]

Acta Alimentaria, 2018
Meriç River Delta is located in the Thrace Region of Turkey, and it is one of the most important wetlands worldwide. Gala and Sığırcı Lakes, which are known as significant lakes in Turkey in terms of especial biodiversity, are located in the Meriç River Delta and they are the main lentic factors of the system.
openaire   +3 more sources

Mammals of Gala Lake National Park

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2019
Gala Lake National Park (GLNP) consists of terrestrial and aquatic ecosystems covering 6.087 hectares of area in Enez and İpsala district boundaries of Edirne province. Extensive field studies were performed on mammals within the boundaries of GLNP for 26 days from 29 July to 07 November 2016.
openaire   +3 more sources

Metazoan parasites of fish species from Lake Gala (Edirne, Turkey)

Ege Journal of Fisheries and Aquatic Sciences, 2014
Turkiye’nin kuzey-batisinda yer alan oytrofik ozellikteki Gala Golu baliklarinin parazitleri bilinmemektedir, bu nedenle arastirmamizda golde bulunan baliklarin metazoan parazitleri arastirilmistir. Temmuz 2010 ve Haziran 2011 tarihleri arasinda Gala Golu’nde bulunan 16 balik turunden toplam 497 ornekle calisildi. Bu baliklarda 53 metazoan parazit turu
openaire   +2 more sources