Results 161 to 170 of about 425,962 (317)

Inside Arthur Lakes Library, Vol.12, Issue 1, Fall 2014

open access: yes, 2014
Inside Arthur Lakes Library is the newsletter of the Colorado School of Mines Arthur Lakes Library and is published twice per academic ...

core  

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

Inside Arthur Lakes Library, Vol.16, Issue 2, Spring 2019

open access: yes, 2019
Inside Arthur Lakes Library is the newsletter of the Colorado School of Mines Arthur Lakes Library and is published twice per academic ...

core  

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

open access: yesAdvanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl   +20 more
wiley   +1 more source

Inside Arthur Lakes Library, Vol.6, Issue 2, Spring 2009

open access: yes, 2009
Inside Arthur Lakes Library is the newsletter of the Colorado School of Mines Arthur Lakes Library and is published twice per academic ...

core  

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu   +9 more
wiley   +1 more source

Inside Arthur Lakes Library, Vol.14, Issue 2, Spring 2017

open access: yes, 2017
Inside Arthur Lakes Library is the newsletter of the Colorado School of Mines Arthur Lakes Library and is published twice per academic ...

core  

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