Results 31 to 40 of about 179,344 (305)
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
Frontiers in Veterinary Science, 2021 Objective: To evaluate the effect of a single administration of 6 and 12 g of Fortetropin compared to placebo on serum myostatin in healthy, adult dogs over a 72-h period.Methods: Prospective, placebo-controlled, randomized, double-blind, crossover study.
Carmella C. Nugent Britt +2 more
doaj +1 more source
Consumer Perception of the Quality of Lamb and Lamb Confit [PDF]
Foods, 2018 The patterns of food consumption in general and those of meat, in particular, are constantly changing. These changes are due not only to socio-economic and cultural trends that affect the whole society but also to the specific lifestyles of consumer groups.
Guillermo Ripoll +2 more
openaire +5 more sources
Advanced Science, EarlyView.A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan +13 more
wiley +1 more source
Mutual Interactions of Lamb Waves in Nonlinear Elastic Plates
Metals, 2022 The mutual interactions of Lamb waves in nonlinear elastic plates are studied in this article. Many researchers have investigated the interactions of Lamb wave modes at nonlinear higher harmonics.
Shuyi Ma +3 more
doaj +1 more source
ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland
Advanced Science, EarlyView.In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu +11 more
wiley +1 more source
Ruminations Regarding Characteristics of Quintessential Adult Communicative Play
Behavioral SciencesGreene and Pruim’s (2023) theory of adult communicative play (TACP) was developed as an effort to address considerations of: (a) pattern and novelty, (b) interpersonal connection, and (c) enjoyment as they pertain to adult conversational activities by ...
John O. Greene
doaj +1 more source
Advanced Energy Materials, EarlyView.Bio‐based gel polymer electrolytes promise sustainable, mechanically adaptable zinc–air batteries, yet their progress is constrained by inconsistent characterization. This review critically links formulation, structure, interfaces, and cell performance, identifies methodological gaps under alkaline operating conditions, and proposes application ...
Matteo Milanesi +6 more
wiley +1 more source
Food Science of Animal Resources, 2019 In this study, the changes in microbial communities of lamb meat packaged in the air (plastic tray, PT) and in a vacuum pouch (VAC) were assessed by polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) during the storage at 4°C ...
Taojun Wang +7 more
doaj +1 more source