Results 221 to 230 of about 3,337,531 (282)

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Experiments on Nonlocal Fluid‐Flow Metamaterials

Advanced Science, EarlyView.
A nonlocal fluid‐flow metamaterial composed of standard microfluidic tubes and connectors is designed. Hence, the current of the system at one position depends on the gradient of fluid flow at many other positions, leading to unusual alternating backward and forward laminar flows of water.
Ke Wang, Yi Chen, Martin Wegener
wiley   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids

Advanced Science, EarlyView.
This study introduces photothermally actuated microcantilevers combined with optical microscopy to simultaneously measure morphology, mass, and mechanical properties of cellular systems in real‐time. The findings link cytoplasm‐dominated mechanical energy dissipation to the Q‐factor as a novel biophysical parameter.
Ilaria Incaviglia, Giulia E. M. Ammirati, Sophie Herzog, Tommy Krug, Nico Strohmeyer, Miguel Camacho Rufino, Matthias P. Lutolf, David A. Weitz, Daniel J. Müller   +8 more
wiley   +1 more source

Laminar Flow Control

The Journal of the Japan Society of Aeronautical Engineering, 1962
openaire   +1 more source

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Electrosynthesis in Laminar Flow Using a Flow Microreactor

The Chemical Record, 2021
AbstractElectrosynthesis and microflow synthesis have become essential tools in their own rights in modern organic synthesis. In this personal account, we summarize our works on the integrated use of these techniques, i. e., electrosynthesis in a flow microreactor.
Naoki Shida, Yuto Nakamura, Mahito Atobe
openaire   +2 more sources

Natural Laminar Flow and Laminar Flow Control

1992
The present volume discusses the development history and basic concepts of laminar flow control, laminar flow flight experiments, subsonic laminar-flow airfoils, and a design philosophy for long-range laminar flow-control commercial transports with advanced supercritical airfoils.
openaire   +1 more source

Laminar Flow in Tubes with Constriction

The Physics of Fluids, 1972
To understand the abnormal flow conditions caused by the presence of stenoses in arteries, an analytical solution is obtained for the steady laminar flow of an incompressible Newtonian fluid in an axisymmetric conduit with irregular surface where the spread of the surface roughness is large compared with the mean radius of the conduit.
Chow, Joseph C. F., Soda, Kunihisa
openaire   +2 more sources

Flow Laminarization and Acceleration by Suspended Particles

SIAM Journal on Applied Mathematics, 2015
In [Comm. Appl. Math. Comput. Sci., 4 (2009), pp. 153-175], Barenblatt presents a model for partial laminarization and acceleration of shear flows by the presence of suspended particles of different sizes, and provides a formal asymptotic analysis of the resulting velocity equation. In the present paper we revisit the model.
BERTSCH, MICHIEL, Hulshof, J, Prostokishin, VM   +2 more
openaire   +3 more sources

LAMINAR AND TURBULENT FLOW

2023
There are numerous approaches to visually represent flow patterns, whether they involve laminar or turbulent flows. A highly compelling method to illustrate these distinctions involves observing the disturbances occurring on the surface of a water stream emerging from a cylindrical tube. Captured through flash photography, these images vividly showcase
Dr. P. Sreenivasulu, Dr. M. Paul Daniel, Daggubati Sunil, D. Raveendra   +3 more
openaire   +1 more source