Results 31 to 40 of about 110,340 (304)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Investigation of spiral blood flow in a model of arterial stenosis [PDF]

open access: yes, 2009
The spiral component of blood flow has both beneficial and detrimental effects in human circulatory system [Stonebridge PA, Brophy CM. Spiral laminar flow in arteries? Lancet 1991; 338: 1360–1].
Paul, M.C., Larman, A.
core   +1 more source

The History of the Slotted Natural-Laminar-Flow Airfoil for Improved Fuel Efficiency

open access: yesAerospace
It is well established that increasing vehicle efficiency enables the achievement of N + 3 sustainable air travel goals. To this end, the integration of a slotted natural-laminar-flow airfoil with a transonic, truss-based commercial wing configuration is
Sreya Kumpatla   +2 more
doaj   +1 more source

Unified Friction Formulation from Laminar to Fully Rough Turbulent Flow

open access: yesApplied Sciences, 2018
This paper provides a new unified formula for Newtonian fluids valid for all pipe flow regimes from laminar to fully rough turbulent flow. This includes laminar flow; the unstable sharp jump from laminar to turbulent flow; and all types of turbulent ...
Dejan Brkić, Pavel Praks
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Numerical investigation of laminar flow in micro-tubes with designed surface roughness [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Elsayed, AM   +4 more
core  

Stress and Vascular Responses: Atheroprotective Effect of Laminar Fluid Shear Stress in Endothelial Cells: Possible Role of Mitogen-Activated Protein Kinases

open access: yesJournal of Pharmacological Sciences, 2003
Atherosclerosis preferentially occurs in areas of turbulent blood flow and low fluid shear stress, whereas laminar blood flow and high shear stress are atheroprotective.
Masanori Yoshizumi   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

First European forum on laminar flow technology Proceedings [PDF]

open access: yes, 1992
Increasing competition in the aircraft market, stringent environmental requirements and increasing air traffic control problems challenge the aeronautical research on all levels, Universities, Research Institutes and Industry.
Deutsche Gesellschaft fuer Luft- und Raumfahrt e.V., Bonn (Germany)
core  

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