Results 61 to 70 of about 4,815,416 (373)

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó, Igor Stevanovski, Germán Morís, Roger Collet‐Vidiella, Alba Segarra‐Casas, Lidia González‐Quereda, Benjamín Rodríguez‐Santiago, Pia Gallano, Rodrigo Alvarez, Ana Vesperinas, Rosa Blanco, Beatriz San‐Millán, Carmen Navarro, Isabel Illa, Gianina Ravenscroft, Ira W. Deveson, Eduard Gallardo, Montse Olivé   +17 more
wiley   +1 more source

Method for the evaluation of minor losses in pulsatile laminar fluid flow

EPJ Web of Conferences, 2014
This article focuses on description and evaluation of the size of the minor losses in pulsatile laminar flow. It describes a method for determination of minor losses with respect to the phase delay between pressure waveforms and flow waveforms. The whole
Netřebská H., Matěcha J., Schmirler M., Manoch L., Adamec J.   +4 more
doaj   +1 more source

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler, Aleksandra Maleska Maceski, Sofia Sandgren, Johanna Oechtering, Sabine Schaedelin, Lisa Hofer, Amar Zadic, Juan Francisco Vilchez Gomez, Lester Melie‐Garcia, Alessandro Cagol, Riccardo Galbusera, Sebastian Finkener, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D’Souza, Lars G. Hemkens, Tobias Derfuss, Özgür Yaldizli, Patrick Roth, Claudio Gobbi, David Brassat, Björn Tackenberg, Henrik Zetterberg, Tjalf Ziemssen, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Fredrik Piehl, Ludwig Kappos, Cristina Granziera, Ahmed Abdelhak, David Leppert, Eline A. J. Willemse, Pascal Benkert, Jens Kuhle, Swiss Multiple Sclerosis Cohort Study (SMSC)   +43 more
wiley   +1 more source

Foam generation in a rotor—stator mixer = Schaumerzeugung in einem rotor—stator mischer [PDF]

, 1988
The foaming process of an aqueous liquid system with surface active agents and thickeners in a rotor-stator mixer has been studied.\ud \ud The foaming capacity of a rotor—stator mixer may be represented by a so-called mixing characteristic.
Bertlein, E., Groot Wassink, J., Kroezen, A.B.J.   +2 more
core   +2 more sources

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Cigarette smoke extract counteracts atheroprotective effects of high laminar flow on endothelial function

Redox Biology, 2017
Tobacco smoking and hemodynamic forces are key stimuli in the development of endothelial dysfunction and atherosclerosis. High laminar flow has an atheroprotective effect on the endothelium and leads to a reduced response of endothelial cells to ...
Sindy Giebe, Natalia Cockcroft, Katherine Hewitt, Melanie Brux, Anja Hofmann, Henning Morawietz, Coy Brunssen   +6 more
doaj  

Investigation and Design of the Transonic Laminar Flow Characteristics in a Laminar Aircraft

Applied Sciences, 2022
Reducing drag is critical to aircraft design. In recent years, laminar technology has become one of the most important feasible technologies for civil aircraft drag reduction design under many design constraints.
Xiaotian Niu, Jie Li
doaj   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

Advanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani, Aditi Singh, Behnam Ashrafi   +2 more
wiley   +1 more source

Changing of energy dissipation in the transition of laminar flow to turbulence (rus) [PDF]

Инженерно-строительный журнал, 2011
Under the same fixed dynamical boundary conditions the energy dissipation in laminar and turbulent flow are compared. As examples the flow past a plate and the flow through a pipe are considered.
Girgidov A.D.
doaj  

An Investigation of Parallel Post-Laminar Flow through Coarse Granular Porous Media with the Wilkins Equation

Energies, 2018
Behaviour of flow resistance with velocity is still undefined for post-laminar flow through coarse granular media. This can cause considerable errors during flow measurements in situations like rock fill dams, water filters, pumping wells, oil and gas ...
Ashes Banerjee, Srinivas Pasupuleti, Mritunjay Kumar Singh, G.N. Pradeep Kumar   +3 more
doaj   +1 more source