Results 31 to 40 of about 990,263 (287)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Cutout reinforcements for shear loaded laminate and sandwich composite panels [PDF]

, 2008
This paper presents the numerical and experimental studies of shear loaded laminated and sandwich carbon/epoxy composite panels with cutouts and reinforcements aiming at reducing the cutout stress concentration and increasing the buckling stability of
Guo, Shijun J., Zhou, L., Cheung, C. W.
core   +1 more source

Multivariate statistical analysis for damage and delamination in composite structures [PDF]

, 2013
The article is devoted to the analysis of the vibration response of composite laminates .Our aim is to develop a method for analysis of the vibration response of structures made of composites which will also be used to develop a vibration-based health ...
Trendafilova, Irina, Garcia, David
core   +3 more sources

Buckling Analysis of Laminated Composite Panel with Elliptical Cutout Subject to Axial Compression

Modelling and Simulation in Engineering, 2012
A buckling analysis has been carried out to investigate the response of laminated composite cylindrical panel with an elliptical cutout subject to axial loading. The numerical analysis was performed using the Abaqus finite-element software. The effect of
Hamidreza Allahbakhsh, Ali Dadrasi
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

In-situ Analysis of Laminated Composite Materials by X-ray Micro-Computed Tomography and Digital Volume Correlation [PDF]

, 2013
The complex mechanical behaviour of composite materials, due to internal heterogeneity and multi-layered composition impose deeper studies. This paper presents an experimental investigation technique to perform volume kinematic measurements in composite ...
Dupré, J.C., Doumalin, Pascal, Germaneau, Arnaud, Brault, Romain, Fazzini, Marina, Brault, R., Doumalin, P., Mistou, Sébastien, Germaneau, A., Dupré, Jean-Christophe   +9 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Rubber Impact on 3D Textile Composites [PDF]

, 2011
A low velocity impact study of aircraft tire rubber on 3D textile-reinforced composite plates was performed experimentally and numerically. In contrast to regular unidirectional composite laminates, no delaminations occur in such a 3D textile composite ...
DUPLESSIS KERGOMARD, Yann, DAU, Frédéric, Benoit Malherbe, Sebastian Heimbs, Frederic Dau, VAN DEN BROUCKE, Björn, Björn Van Den Broucke, MALHERBE, Benoit, Yann Duplessis Kergomard, HEIMBS, Sebastian   +9 more
core   +1 more source

The Mechanical Properties of Laminated Composites Reinforced With Discontinuous and Continuous Different Fibers

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
 In this paper we investigate how do the laminated composites behave mechanically when subjected to external stresses, when reinforced with continuous fibers (mat) and discontinuous fibers (chopped) and to find the effect of the fiber type on the ...
M. A. ` AL-Nesearawi
doaj