Results 101 to 110 of about 39,751 (287)

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Development of the DKMQ Element for Analysis of Composite Laminated Folded Plate Structures [PDF]

, 2018
The discrete-Kirchhoff Mindlin quadrilateral (DKMQ) element has recently been developed for analysis of composite laminated plates. This paper presents further development of the DKMQ for analysis of composite laminated folded plates. In this development,
Tjong, Wong Foek, WIDJAJA, KRISTOFER
core  

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Transient analysis of laminated composite plates using NURBS-based isogeometric analysis

Vietnam Journal of Mechanics, 2014
We further study isogeometric approach for response analysis of laminated composite plates using the higher-order shear deformation theory. The present theory is derived from the classical plate theory (CPT) and the shear stress free surface conditions ...
Lieu B. Nguyen, Chien H. Thai, Ngon T. Dang, H. Nguyen-Xuan   +3 more
doaj   +1 more source

DYNAMIC ANALYSIS OF LAMINATED COMPOSITE PLATES

International Journal of Research in Engineering and Technology, 2015
In the recent years, the use of laminated composite plates has been increased considerably. Fiber reinforced composites are finding increasing applications in the aerospace, marine, transportation, electrical, chemical, construction and consumer goods industries. In many of these applications, the composites are often subjected to dynamic loads. Hence,
openaire   +1 more source

Three‐Dimensional Ovary Model to Improve and Study Murine Follicle Growth

Advanced Healthcare Materials, EarlyView.
To develop new methods for fertility preservation in women, novel culture systems for small follicles need to be established. In this work, a poly(ethylene glycol) based scaffold, with appropriate mechanical and bioactive features to support mouse follicle and ovary cell growth is developed, and the formed cell‐follicle interactions are visualized ...
Mira Jacobs, Valon Gllareva, Lukas Moser, Silvia Pravato, Eric Mora Pimentel, Brigitte Leeners, Martin Ehrbar   +6 more
wiley   +1 more source

Application of piezoelectric macro-fiber-composite actuators to the suppression of noise transmission through curved glass plates

, 2012
This paper analyzes the possibility of increasing the acoustic transmission loss of sound transmitted through planar or curved glass shells using attached piezoelectric macro fiber composite (MFC) actuators shunted by active circuits with a negative ...
Mokry, Pavel, Novakova, Katerina, Vaclavik, Jan   +2 more
core   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

The effect of temperature on the vibration behavior of laminated composite plates

International Journal of Applied Mechanics and Engineering
The present work is a contribution to the study of the effects of temperature on vibrations and stability of laminated composite plates using the finite element method. Thus, a DMQP/ml bending finite element with 4 nodes and 3 degrees of freedom based on
Mohamed lamine SALHI, Houdayfa OUNIS, Mekki MELLAS   +2 more
doaj   +1 more source