Results 41 to 50 of about 34,899 (244)

Comparison of posterior decompression techniques and conventional laminectomy for lumbar spinal stenosis

open access: yesFrontiers in Surgery, 2022
ObjectivesTo compare the efficacy of posterior decompression techniques with conventional laminectomy for lumbar spinal stenosis.MethodsThe Embase, PubMed, and Cochrane Library databases were searched with no language limitations from inception to ...
Yong Zhang   +6 more
doaj   +1 more source

Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi   +16 more
wiley   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu   +9 more
wiley   +1 more source

Comparison of Spinous Process-Splitting Laminectomy versus Conventional Laminectomy for Lumbar Spinal Stenosis [PDF]

open access: yesAsian Spine Journal, 2014
Study DesignSeventy-five patients who had been treated for lumbar spinal stenosis (LSS) were reviewed retrospectively.PurposeInvasion into the paravertebral muscle can cause major problems after laminectomy for LSS.
Masashi Uehara   +10 more
doaj   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

open access: yesAdvanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen   +11 more
wiley   +1 more source

Establishment and multifaceted characterization of a graded spinal cord injury model based on graduated impact depth

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established a graded spinal cord injury (SCI) model based on graduated impact depth, which was subsequently characterized across multiple dimensions, including locomotor function, imaging, histology, and transcriptomic profiles. We further identified transcriptomic changes in graded SCI at different time points postinjury and investigated the ...
Gang Zhou   +6 more
wiley   +1 more source

The effect of oophorectomy on epidural fibrosis after laminectomy: an experimental study in rats

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objective: The aim of this study was to examine the effect of oophorectomy in the formation of epidural fibrosis in a rat laminectomy model. \r\nMethods: Thirty-six 12-month-old adult female Sprague-Dawley rats were used in this study.
Esra Circi   +5 more
doaj   +1 more source

Role of COL1A1 and CD44 in Modulating JAK1/STAT3‐Mediated Autophagy for Spinal Cord Injury Recovery

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Spinal cord injury (SCI) is a severe trauma to the central nervous system that often leads to motor and sensory dysfunction in patients, severely affecting their quality of life. Autophagy plays a role in the pathological process of SCI, but the specific mechanism of autophagy in this case is unknown.
Chun‐Lei Li   +3 more
wiley   +1 more source

Prospective analysis of surgical outcomes in patients undergoing decompressive laminectomy and posterior instrumentation for degenerative lumbar spinal stenosis

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objectives: The aim of this study was to evaluate the outcome of wide surgical decompression and concomitant posterior instrumentation in patients with degenerative lumbar spinal stenosis.\r\nMethods: Thirty-seven consecutive patients (14 men, 23 women ...
Ioannis D. Gelalis   +5 more
doaj   +1 more source

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