Results 41 to 50 of about 36,451 (229)

Wide Laminectomy, Segmental Bilateral Laminotomies, or Unilateral Hemi-Laminectomy for Lumbar Spinal Stenosis

, 2021
STUDY DESIGN: Propensity-matched retrospective study of patients prospectively enrolled in Danespine. OBJECTIVE: The aim of this study was to report 5-year patient reported outcome in lumbar spinal stenosis (LSS) patients who underwent wide laminectomy ...
Stig Brorson, Leah Y. Carreon, Mikkel Østerheden Andersen, Carreon, Leah Y., Andersen, Mikkel Østerheden; id_orcid, Pedersen, Casper Friis, Bouknaitir, Jamal Bech, Brorson, Stig, Andersen, Mikkel Østerheden, Carreon, Leah Y, Jamal Bech Bouknaitir, Casper Friis Pedersen   +11 more
core   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Recapping laminoplasty versus laminectomy (six months postoperatively).

, 2014
The range of motion (with one standard deviation error bar) for the INT, recapping laminoplasty (abbreviated as laminoplasty) and laminectomy conditions for the three rotation planes. *Significant difference between intact and laminectomy.
Tao Yu (176965), Jia Zhang (187802), Hua Zhang (12549), Guo zhong Lin (580935), Yu Si (580933), Zhenyu Wang (580934), Yuan chao Li (580936), Kuo Zhang (337825)   +7 more
core   +1 more source

Patient outcomes after laminotomy, hemilaminectomy, laminectomy and laminectomy with instrumented fusion for spinal canal stenosis: a propensity score-based study from the Spine Tango registry [PDF]

, 2021
Purpose: To compare patient outcomes and complication rates after different decompression techniques or instrumented fusion (IF) in lumbar spinal stenosis (LSS). Methods: The multicentre study was based on Spine Tango data.
Sobottke, Rolf, Munting, Everard, Röder, Christoph, Dietrich, Daniel, Aghayev, Emin   +4 more
core  

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Laminectomy alone versus laminectomy with fusion for degenerative cervical myelopathy : a long-term study of a national cohort

, 2022
PURPOSE: To compare patient-reported 5-year clinical outcomes between laminectomy alone versus laminectomy with instrumented fusion in patients with degenerative cervical myelopathy in a population-based cohort.
Heary, Robert F., de Dios, Eddie,, de Dios, Eddie, MacDowall, Anna,, Lindhagen, Lars, Lindhagen, Lars,, MacDowall, Anna   +6 more
core   +1 more source

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Study on Results of Laminectomy with Short-Segment Pedicle Screw Fixation in Dorsolumbar Fractures with Respect to Anatomical Reduction, Functional Recovery and Pain

Journal of Bone and Joint Diseases, 2023
Background: The aim of this study was to report the results of laminectomy with short-segment pedicle screw fixation in thoracolumbar fracture. Materials and Methods: Forty-two patients were analyzed prospectively, followed up in the outpatient ...
Deepanshu Maheshwari, Gyaneshwar Tonk, Sumit Agarwal   +2 more
doaj   +1 more source

Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy

Advanced Science, EarlyView.
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li, Ruixiao Hu, Jie Mao, Jin Wo, Yunsong Zhang, Liang Chen, Ying Liu, Zhibo Li, Yongxin Lin, Minghui Du, Yaofei Chen, Libing Zhou, Tuan Guo   +12 more
wiley   +1 more source

Late laminectomy in traumatic paraplegia

, 1983
Long-term observation in cases of spinal injury with sub-arachnoid block, treated by laminectomy and removal of compressing elements, shows worthwhile results in a good percentage.
Ramamurthi, Ravi, Narayanan, R., Ramamurthi, B.   +2 more
core   +1 more source