Results 71 to 80 of about 65,008 (311)

Targeted Perfusion Therapy in Spinal Cord Trauma. [PDF]

, 2020
We review state-of-the-art monitoring techniques for acute, severe traumatic spinal cord injury (TSCI) to facilitate targeted perfusion of the injured cord rather than applying universal mean arterial pressure targets.
Papadopoulos, MC, Saadoun, S
core   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

Treatment of the Fractional Curve of Adult Scoliosis With Circumferential Minimally Invasive Surgery Versus Traditional, Open Surgery: An Analysis of Surgical Outcomes. [PDF]

, 2018
Study Design:Retrospective, multicenter review of adult scoliosis patients with minimum 2-year follow-up. Objective:Because the fractional curve (FC) of adult scoliosis can cause radiculopathy, we evaluated patients treated with either circumferential ...
Anand, Neel, Chou, Dean, Deviren, Vedat, Eastlack, Robert, Fessler, Richard, Fu, Kai-Ming, International Spine Study Group, Kanter, Adam, La Marca, Frank, Mummaneni, Praveen, Mundis, Gregory, Nguyen, Stacie, Nunley, Pierce, Okonkwo, David, Park, Paul, Than, Khoi, Uribe, Juan, Wang, Michael, Zavatsky, Joseph   +18 more
core   +1 more source

Survivorship of Individuals With Double Heterozygosity for Achondroplasia and Type 2 Collagenopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Historically, double heterozygosity, or a diagnosis of two separate, dominant genetic conditions, was often thought to be lethal in individuals with autosomal dominant skeletal dysplasias. In previously published studies of individuals with dual dysplasia diagnoses of achondroplasia and type 2 collagenopathy, infants died of respiratory ...
Valerie R. Schwartz, Andrea Schelhaas, Angela L. Duker, Ricki S. Carroll   +3 more
wiley   +1 more source

Bioresorbable Film for the Prevention of Adhesion to the Anterior Spine After Anterolateral Discectomy [PDF]

, 2009
Background context The development of scar tissue and adhesions postoperatively is a natural consequence of healing but can be associated with medical complications and render reoperation difficult.
Klopp, Lisa S., Rao, Sangeeta, Tai, Joseph W., Thomas, Kevin A., Toth, Jeffrey M., Turner, Simon, Welch, William C.   +6 more
core   +1 more source

Lumbar Laminectomy in the Outpatient Setting Is Associated With Lower 30-Day Complication Rates

Global Spine Journal, 2019
Study Design: Retrospective cohort study. Objectives: To compare the incidence of complications in patients undergoing single-level and 2-level lumbar laminectomy in either the inpatient or outpatient settings.
T. Karukonda, Nickolas S. Mancini, A. Katz, M. Cote, I. Moss   +4 more
semanticscholar   +1 more source

Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice

Glia, EarlyView.
ABSTRACT Spinal cord injury (SCI) results in significant disruption of nerve fibers responsible for transmitting signals between the brain and body, often leading to partial or complete motor, sensory, and autonomic dysfunction below the injury site. Astrocytes are an important component in scar formation, crucial for suppression of injury propagation,
Barbora Smejkalová, Marta Ornaghi, Kateřina Štěpánková, Juliane Schiweck, Lucia Machová Urdzíková, Robert Huelse, Susanne Mueller, Philipp Boehm‐Sturm, Jessica C. F. Kwok, James Fawcett, Kai Murk, Britta J. Eickholt, Pavla Jendelová   +12 more
wiley   +1 more source

Skip laminectomy versus cervical laminectomy, an analysis of patient reported outcomes, spinal alignment and re-operation rates: The Leeds spinal unit experience (2008–2016)

Interdisciplinary Neurosurgery, 2019
The two leading techniques in the UK utilised in the posterior decompression of the cervical spinal cord for cervical spondylotic myelopathy (CSM) are skip laminectomy (Skip LAMT) and open cervical laminectomy (LAMT). To the authors' knowledge no studies
James M.W. Robins, MRCS, Lorna Luo, Fatmah Mallallah, Jake Timothy, MD FRCS, Deb Pal, FRCS, Chris Derham, MD FRCS, Senthil K. Selvanathan, FRCS   +6 more
doaj  

Combined Anterior and Posterior Decompression With Fusion for Cervical Ossification of the Posterior Longitudinal Ligament

Frontiers in Surgery, 2022
Objective:Cervical myelopathy caused by ossification of the posterior longitudinal ligament (OPLL) is not uncommon among Asian ethnic groups. Despite reports comparing the pros and cons of anterior- and posterior-only approaches, the optimal management ...
Chao-Hung Kuo, Chao-Hung Kuo, Chao-Hung Kuo, Yi-Hsuan Kuo, Yi-Hsuan Kuo, Chih-Chang Chang, Chih-Chang Chang, Chih-Chang Chang, Hsuan-Kan Chang, Hsuan-Kan Chang, Hsuan-Kan Chang, Li-Yu Fay, Li-Yu Fay, Li-Yu Fay, Jau-Ching Wu, Jau-Ching Wu, Wen-Cheng Huang, Wen-Cheng Huang, Henrich Cheng, Henrich Cheng, Tsung-Hsi Tu, Tsung-Hsi Tu   +21 more
doaj   +1 more source

Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects

Interdisciplinary Medicine, EarlyView.
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu, Zhendong Huang, Xiner Tan, Wei Du, Ziyang Wang, Xinru Zhou, Hao Pan, Lili Chen, Yiyuan Kang, Longquan Shao   +9 more
wiley   +1 more source