Results 161 to 170 of about 108,751 (260)

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Apical-out polarity in epithelial spheroids requires α6β4 integrins, cell proliferation and anchorage independence. [PDF]

J Cell Sci
Patel N, Pirrello J, Lynch S, Patel H, Sweeney BJ, Priya S, Lele TP, Manninen A, Conway DE.   +8 more
europepmc   +1 more source

A horizontally transferred bacterial gene for pantothenic acid biosynthesis regulates diapause and reproduction in the spider mite Amphitetranychus viennensis

Insect Science, EarlyView.
A bacterial‐derived AvPBL gene encoding a pantothenate‐β‐alanine ligase was identified in Amphitetranychus viennensis. RNAi silencing of AvPBL reduced pantothenic acid production, impairing reproduction and diapause induction, while pantothenic acid supplementation rescued these phenotypes.
Meibin Liu, Yifei Wang, Yikang Ren, Fan Yang, Meifeng Ren, Qin Yu, Xuguo Zhou, Zezhong Yang, Jing Yang   +8 more
wiley   +1 more source

Effect of Fibronectin and Laminin on Compaction of Myoblast-Seeded Collagen Hydrogels. [PDF]

J Funct Biomater
Sicherer ST, Guliani J, Raju SA, Parikh Y, Martin C, Pridmore J, Coombs K, Grasman JM.   +7 more
europepmc   +1 more source

A Systematic Review of Topical and Systemic Gentamicin for Wound Healing in Patients With Junctional and Dystrophic Epidermolysis Bullosa

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Epidermolysis bullosa (EB) is an inherited mechanobullous genodermatosis caused by a mutation in genes encoding proteins integral to skin integrity. Premature termination codon readthrough therapies, such as gentamicin, have promise in facilitating full‐length protein expression in patients with EB.
Kelvin Truong, Joseph Joseph, Deborah Poh, Orli Wargon, Artiene Tatian   +4 more
wiley   +1 more source

Laminin - myCAF interplay promotes α6-integrin-mediated breast cancer cell invasion.

Lab Chip
Virumbrales-Muñoz M, Fertal SA, Lugo-Cintrón KM, Loken JR, Numan-Vazquez Y, Burkel BM, Zhang J, Franck C, Ayuso JM, Beebe DJ, Ponik SM.   +10 more
europepmc   +1 more source

A case of anti-laminin 332-type mucous membrane pemphigoid mimicking linear IgA bullous dermatosis. [PDF]

JAAD Case Rep
Du X, Dang J, Zhao J, Shang P.
europepmc   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Temperature Replica-Exchange Molecular Dynamics Reveals a Heterogeneous Recognition-Compatible Ensemble of the Laminin-Derived Peptide CDPGYIGSR. [PDF]

Biomolecules
Di Giovanni C, Lavecchia A.
europepmc   +1 more source