Results 51 to 60 of about 7,460,005 (287)

The Effect of the Human Footprint and Climate Change on Landscape Ecological Risks: A Case Study of the Loess Plateau, China

Land, 2022
The increase in ecological risks caused by human activities has become a global concern in recent years. The Landscape Ecological Risk Index based on the theory of landscape ecology is more suitable for assessing large-scale ecological risks.
Zhi Qu, Yonghua Zhao, Manya Luo, Lei Han, Shuyuan Yang, Lei Zhang   +5 more
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Ecological Risk Assessment and Prediction Based on Scale Optimization—A Case Study of Nanning, a Landscape Garden City in China

, 2023
Analysis and prediction of urban ecological risk are crucial means for resolving the dichotomy between ecological preservation and economic development, thereby enhancing regional ecological security and fostering sustainable development. This study uses
Guoqing Zhou, Jianjun Chen, Renjie Huang, Zihao Feng, Yanping Yang, Haotian You, Xiaowen Han   +6 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Flood-Landscape Ecological Risk Assessment under the Background of Urbanization [PDF]

Water, 2019
The Hydrologic Modeling System (HEC-HMS) and statistical analysis method were used to analyze the relationship between flood eigenvalues (i.e., flood volume and peak flow) and landscape pattern metrics. Then, the flood-landscape ecological risk index (ERI_FL) was proposed and constructed to quantitatively assess the flood-landscape ecological risk ...
Yu Yuan, Guohua Fang, Min Yan, Chunming Sui, Ziyu Ding, Chengxuan Lu   +5 more
openaire   +2 more sources

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

Advanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang, Nan Zhang, Xisong Liang, Jie Wen, Ziyu Dai, Wantao Wu, Shuyu Li, Songshan Feng, Zaoqu Liu, Zhiwei Xia, Peng Luo, Quan Cheng   +11 more
wiley   +1 more source

Assessing Landscape Ecological Risk from Mining in the River Source Region of the Yellow River Basin

Land
The river source region of the Yellow River Basin is a critical ecological barrier in China, yet it is characterized by extreme environmental vulnerability. Human activities, particularly intensive mining, can severely disrupt the landscape ecosystem and
Wenjia Xu, Weiling Yao, Hao Wang, Jinzhong Yang, Tiantian Yu, Hang Yu   +5 more
doaj   +1 more source

Landscape Ecological Risk Characteristics of Three Gorges Reservoir Area Based on Terrain Gradient

Shuitu baochi yanjiu, 2023
Landscape ecological risk assessment can better reflect the negative impact of external stressors on the ecosystem, and analyze the distribution characteristics of landscape ecological risk levels on the terrain gradient, which can provide scientific ...
LI Xin, YANG Chaoxian, XIN Guixin, YANG Kui, JIANG Haoyu   +4 more
doaj  

Proceedings of the 10th International Conference on Ecological Informatics: translating ecological data into knowledge and decisions in a rapidly changing world: ICEI 2018 [PDF]

, 2018
The Conference Proceedings are an impressive display of the current scope of Ecological Informatics. Whilst Data Management, Analysis, Synthesis and Forecasting have been lasting popular themes over the past nine biannual ICEI conferences, ICEI 2018 ...
International Conference on Ecological Informatics
core   +1 more source