Results 71 to 80 of about 4,811,914 (285)
Constraints on the spectral index for the inflation models in the string landscape [PDF]
We conjecture that the inflation models with trans-Planckian excursions in the field space should be in the swampland. We check this conjecture in a few examples and investigate the constraints on the spectral index for the slow-roll inflation model in string landscape where the variation of inflaton during the period of inflation is less than the ...
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Comparisons of the accuracy and consistency of different remote-sensing land cover datasets are important for the rational application of multi-source land cover datasets to regional development, or to studies of global or local environmental change ...
Junmei Kang +5 more
doaj +1 more source
Indexing the vulnerability of biotopes to landscape changes
Abstract Biodiversity loss is one of the great challenges of our times, and it is primarily driven by losses of natural and semi-natural areas. To avoid further biodiversity losses, landscape planning and ecosystem management could benefit from a condensed measure that tracks regional and cumulative ecological degradation from past and ongoing ...
openaire +1 more source
A Study on Application of Landscape Diagnosis Index and Landscape Formation Plan of Rural Villages
In this study, it propose what the landscape elements is to be improved urgently and how to improve landscape by reflecting the rural village characteristics away from the spatial integrated landscape planning. The study area for landscape research is selected as the 9 rural villages in Chungcheongbuk-do, and research is done by using village unit ...
Hee-Jung Song +3 more
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The landscapes surrounding power stations commissioned by the nationalised electricity industry and the Central Electricity Generating Board (CEGB) offered significant opportunities for landscape architects in post-war Britain, and had a huge impact on ...
Csepely-Knorr, Luca
core
Intensive mining activities in the Zhungeer open-pit coal mining area of China have resulted in drastic changes to land use and landscape patterns, severely affecting the ecological quality and stability of the region.
Yinli Bi +4 more
doaj +1 more source

