Results 91 to 100 of about 5,176,691 (243)

Landscape Change Index as a Tool for Spatial Analysis

IOP Conference Series: Materials Science and Engineering, 2017
This study analysed spatial and temporal changes in protected landscape of Ślęża Landscape Park in Poland, covering an area of 7724 ha. The main objective was to determine level of landscape change of the research area after Polish accession to European Union by comparing land-cover maps from 2004, 2009 and 2014.
Piotr Krajewski, Iga Solecka, Barbara Mastalska-Cetera   +2 more
openaire   +1 more source

From urban beautification to a holistic approach: the discourses of ‘landscape’ in the Arab Middle East [PDF]

, 2016
: The English word and Western idea of landscape was introduced during the colonial restructuring of Arab cities in the early decades of the twentieth century.
Makhzoumi, Jala M.
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Biodiversity index for landscape

Bulletion of the International Association for Landscape Ecology-Japan, 2000
Tsuyoshi YOSHIDA, Kazuhiro TANAKA
openaire   +3 more sources

Landscape Report for Data Sharing Index

Project Objectives: Identifying metrics that can measure the impact of sharing primary data, including datasets, software tools and sequence data.  Identifying alternative methods to encourage primary data sharing.    
Guemez, Andrea, McLaren, Anne
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Spatial Prediction of Soil Water Content by Bayesian Optimization–Deep Forest Model with Landscape Index and Soil Texture Data

Agronomy
The accurate prediction of the spatial variability for soil water content (SWC) in farmland is essential for water resource management and sustainable agricultural development.
Weihao Yang, Ruofan Zhen, Fanyue Meng, Xiaohang Yang, Miao Lu, Yingqiang Song   +5 more
doaj   +1 more source

Landscape ecology integrates pattern and process in river corridors

, 1999
Landscape ecology holds the potential for developing a truly holistic perspective of river corridors, one that rigorously integrates structure, dynamics, and function.
Tockner, K. (author), Ward, J.V. (author), Malard, F. (author)   +2 more
core