Results 101 to 110 of about 156,624 (263)

Effects of landscape pattern change on waterbird diversity in Xianghai Nature Reserve

open access: yesOpen Geosciences
In order to study the change of landscape pattern and its impact on waterbird diversity in Xianghai Nature Reserve, this article analyzes the changing landscape pattern of the reserve from 2014 to 2017 at the landscape and type level. Pearson correlation
Zhao Yuelan   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Temporal and Spatial Changes of Soil Erosion and Its Response to Landscape Pattern in Dabie Mountains of Western Anhui in Recent 30 Years

open access: yesShuitu Baochi Xuebao
[Objective] The Dabie Mountain area in western Anhui Province is an important ecological transition area between the Yangtze River Basin and the Huaihe River Basin in Anhui Province.
TIAN Changyuan   +5 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Reconciling natural habitat size loss and quality enhancement: the dual effects of urbanization in China’s Loess Plateau

open access: yesEnvironmental Research Letters
Amid accelerating urbanization and severe biodiversity loss in global drylands, reconciling urbanization with habitat conservation is crucial for sustainable development.
Siya Li   +9 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The Landscape Resilience Index: a flexible tool for integrated landscape management

open access: yesFrontiers in Sustainable Food Systems
Globally, landscapes are subject to intensifying and interacting environmental pressures, making landscape resilience increasingly important for sustaining ecosystem services, livelihoods, and long-term development. Integrated landscape management offers
W. Ovenden   +10 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

An Integrated Framework for Landscape Indices’ Calculation with Raster–Vector Integration and Its Application Based on QGIS

open access: yesISPRS International Journal of Geo-Information
Landscape-index calculation tools play a pivotal role in ecosystem studies and urban-planning research, enabling objective assessments of landscape patterns’ similarities and differences.
Yaqi Huang   +4 more
doaj   +1 more source

The landscape disparity index: an ecologically weigthed measure of the landscape diversity

open access: yes, 2007
Typically, the analysis of landscape patterns is based on a quantitative analysis of the composition or/and the spatial arrangements of categorical units mapped from aerial photographs, satellite images or land use maps using so-called landscape metrics (Gustafson, 1998). Usually in landscape studies, authors assume that different landscape habitats or
openaire   +1 more source

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