Results 51 to 60 of about 5,508,906 (294)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Quantitative Landscape Analysis Using Earth-Observation Data: An Example from Chania, Crete, Greece
Pursuing sustainability in a challenging world and under the influence of numerous natural and anthropogenic drivers of change presents one of the major global concerns.
Chariton Kalaitzidis +5 more
core +1 more source
Perspective on the Refractive-Index Gas Metrology Data Landscape
The redefinition of the kelvin has increased focus on thermometry techniques that use the newly fixed value of the Boltzmann constant to realize thermodynamic temperature. One such technique that has advanced considerably in recent years is refractive-index gas thermometry.
openaire +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Architectural landscape index values for each functional land.
Architectural landscape index values for each functional land.
Xina Ma (11883517) +3 more
core +1 more source
In order to explore the spatial distribution differences of traditional village settlements in Guizhou Province, based on five batches of 725 traditional villages in Guizhou Province and 2017 settlement data, the spatial distribution characteristics and ...
YANG Xingyan, ZHAO Cuiwei
doaj
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Dynamic Landscape Fragmentation and the Driving Forces on Haitan Island, China
Island ecosystems have distinct and unique vulnerabilities that place them at risk from threats to their ecology and socioeconomics. Spatially exhibiting the fragmentation process of island landscapes and identifying their driving factors are the ...
Jingwen Ai +4 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The Landscape Resilience Index: a flexible tool for integrated landscape management
Globally, landscapes are subject to intensifying and interacting environmental pressures, making landscape resilience increasingly important for sustaining ecosystem services, livelihoods, and long-term development. Integrated landscape management offers a promising approach to strengthening resilience, yet many existing monitoring frameworks are not ...
W. Ovenden +10 more
openaire +1 more source

