Results 131 to 140 of about 4,814,228 (287)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Azalea Garden, Minnesota Landscape Arboretum Map

open access: yes, 2005
Map of the Minnesota Landscape Arboretum with Woodland Azalea Garden highlighted. Map is undated but depicts the Oswald Visitor Center, which opened in 2005.University of Minnesota. Minnesota Landscape Arboretum. (2005).
University of Minnesota. Minnesota Landscape Arboretum
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

3D modelling in landscape practice in New Zealand

open access: yes, 2013
The profession of landscape architecture has undergone significant change over the last 40 years, both internationally and locally. The New Zealand Institute of Landscape Architects (NZLIA) is keen to establish a profile of landscape architecture in New
Barthelmeh, M
core  

Research on Land Use and Its Landscape Pattern Dynamical Changes Based on RS and GIS in Zhalong Wetland

open access: yesShuitu baochi yanjiu, 2008
Using RS and GIS,the land use range,the prior transfers procedure and contribution,land use degree index and landscape pattern index were used to study the spatial-temperal change of land use based on remote sensing images in 1995,2000 and 2004.we ...
YUAN Li1   +3 more
doaj  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Land use changes, landscape ecology and their socioeconomic driving forces in the Spanish Mediterranean coast (the Maresme County, 1850-2005) [PDF]

open access: yes
We use a set of landscape metrics to study the long-term environmental transformation of a typical coastal Mediterranean area from 1850 to 2005. Our figures show a dramatic environmental deterioration between 1950 and 2005.
Lluis Parcerisas   +5 more
core  

Characteristics of Landscape Pattern and Spatial Distribution of Rural Residential Areas in Baoquanling Reclamation of Heilongjiang Province

open access: yesShuitu baochi yanjiu, 2013
The second land survey data vector data of 2005 was used to analy Bao Quanling reclamation area′s in Heilongjiang Province spatial distribution characteristics to analyze through the method of combining the theory of landscape ecology and the Voronoi CV ...
WANG Shi-yu   +3 more
doaj  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Research on the Land Use Landscape Pattern of Different Soil Types in Central-south Hilly Area

open access: yesShuitu baochi yanjiu, 2012
By using the softwares of RS,GIS and Fragstats,the relationship between soil type and landscape pattern,landscape indices in Liling City was studied.The result showed that:(1) the major soil types in Liling City were red soil and paddy soil,and landscape
WEN Qian1, LI Qing-song1, SUN Shui-juan2
doaj  

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