Results 191 to 200 of about 92,291 (256)

An EHA strategic roadmap for improved care in Europe for AYA patients with malignant and chronic non-malignant hematological diseases. [PDF]

Hemasphere
Castleton A, Batten S, Boissel N, Borowczak Y, Colombatti R, Doeswijk R, Hilgendorf I, McGrath C, Messelink K, Miano M, Yacobovich J, Vormoor HJ.   +11 more
europepmc   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Landscape-socioeconomic feedback mechanisms in Sichuan's river basins. [PDF]

iScience
Shen R, Shu S, Wang Y, Tian Y, Chen W.
europepmc   +1 more source

The current state of electronic health records across Canada: an environmental scan and interoperability maturity assessment. [PDF]

CMAJ
Kannappan S, Hastings S, Forster A, Dean S, Hollett G, Hagens S, Gheorghiu B, Affleck E, Snyman C, Adams O, Williamson T, Manns B.   +11 more
europepmc   +1 more source

Sequencing AI Automation and Data Interoperability in Oncology Using a Scenario-Planning Framework Coupled With Discrete-Event Simulation: Proof-of-Concept Study. [PDF]

J Med Internet Res
May P, Brookman-May SD, Garrahy E, von Büren J.   +3 more
europepmc   +1 more source

Unlocking the Potential of AI and Big Data in Cancer Research: Advances and Applications. [PDF]

Cancers (Basel)
Mastroleo F, Marvaso G.
europepmc   +1 more source