Results 161 to 170 of about 432,625 (307)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Will there be a warning for the next pandemic? [PDF]

Sci Adv
Lessler J, Metcalf CJE.
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Landscapes buried beneath large-volume ignimbrites reveal preeruptive uplift rates. [PDF]

Sci Adv
Adams BA, Cooper FJ, Walsh C, Cashman KV.   +3 more
europepmc   +1 more source

Globalisation - a threat to traditional landscapes and local identity? [PDF]

Traditional landscapes could be considered as one of the most apparent carriers of local identities. They act as memory of previous human activities. During the 1990s the economic changes have had a drastic influence on the appearance of these landscapes.
Hannes Palang, Helen Sooväli, Helen Alumäe   +2 more
core  

The Landscape of Lexicography

, 2019
This book consists of a series of papers that look at three different aspects of the landscape as seen in dictionaries from across Europe. Multilingual diachronic case studies into lexicographical descriptions of fora, landscape features and colours concentrate on three supposedly simple words: daisies (Bellis perenis L.), hills and the colour red. The
Villalva, Alina, Williams, Geoffrey
openaire   +3 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Panmixia in a Widespread Butterfly: High Dispersal and Ecological Generalism Buffer Against Landscape Fragmentation. [PDF]

Ecol Evol
Dhyani P, Deppe F, Fischer K.
europepmc   +1 more source

[Matted Watercolor Landscapes 02]

, 2003
Paddlewheel steamboat on river.Tiff file: 2580x3480 pixels, 25.7 Mb; Display: jpeg, 593x800 pixels ...
Father Edward Catich
core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source