Results 141 to 150 of about 29,666 (295)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Increasing Biochar Yield in Pyrolysis by Adding Ash. [PDF]
Grafmüller J +5 more
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Low-Income, Minority-Serving Public Schools in Southern California Have Disproportionately High Surface Temperatures. [PDF]
Murillo J +3 more
europepmc +1 more source
This book consists of a series of papers that look at three different aspects of the landscape as seen in dictionaries from across Europe. Multilingual diachronic case studies into lexicographical descriptions of fora, landscape features and colours concentrate on three supposedly simple words: daisies (Bellis perenis L.), hills and the colour red. The
Villalva, Alina, Williams, Geoffrey
openaire +3 more sources
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Proactive Initiative to Establish a Dengue-Free Factory Assessment Framework in Dengue High-Risk Industrial Areas: A Narrative Review. [PDF]
Ritthison W +3 more
europepmc +1 more source
Landscaping for Engineers, 1979
Central Gardens landscape.
Swinburne Institute of Technology
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