Results 51 to 60 of about 29,666 (295)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Вісник Харківського національного університету імені В.Н. Каразіна. Серія Геологія. Географія. Екологія, 2021 Formulation of the problem. This article is devoted to the critical topic of modern Urban studies –the river’s role in urban space. There are many projects of the river’s revitalization in the USA, South Korea, and Europe.
Вікторія Нестеренко
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
BMC Plant BiologyThe present investigation was conducted at the Punjab Agricultural University, Ludhiana, during 2022–23 to evaluate twenty genetically diverse chrysanthemum (Chrysanthemum morifolium Ramat.) genotypes demonstrating cut, loose, and pot culture categories ...
Madhu Bala, Komalpreet Kaur
doaj +1 more source
Impact assessment of water and nutrient reuse in hydroponic systems using Bayesian Belief Networks
Journal of Water Reuse and Desalination, 2020 Water-saving agricultural practices can reduce negative environmental impacts in water-scarce regions all over the world. This study deals with an innovation that combines hydroponic crop production and municipal wastewater reuse for irrigation purposes.
Martin Zimmermann, Michaela Fischer
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The behaviour of some hyacinth varieties in forced culture
Acta Universitatis Sapientiae: Agriculture and Environment, 2019 This paper presents the behaviour of five hyacinth varieties: ‘City of Haarlem’, ‘Blue Jacket’, ‘Miss Saigon’, ‘Jan Boss’, and ‘Double Prince of Love’ in forced culture under the influence of different culture substrates.
Székely-Varga Zsolt +4 more
doaj +1 more source