Results 141 to 150 of about 1,841,934 (257)
Advanced Science, EarlyView.The maize BTB/POZ‐MATH (BPM) protein ZmBPM1 interacts with autophagy‐related protein ZmATG6 to relocate the NLR protein Rp1‐D21 from the nucleo‐cytoplasmic compartment into autophagosome‐like puncta, leading to autophagy‐mediated turnover and suppressing the hypersensitive response.
Chang‐Xiao Tang +8 more
wiley +1 more source
Advanced Science, EarlyView.Targeted protein degradation is often limited by the scarcity of usable E3 ligases. Herein, we report the first small‐molecule GPX4 degraders that incorporate either electrophilic warheads or a minimal azide group as an E3 recruitment ligand. The azide‐based degrader DK‐5070 effectively drives potent GPX4 degradation; mechanistic studies reveal that ...
Zehong Lin +14 more
wiley +1 more source
Design for a bedstead : sketch no. 62 [picture] /
, 1926 Part of collection: Furniture designs for Prime Minister's Lodge and Government House, Canberra.; Inscriptions: signed "Ruth Lane-Poole, Oct 30 1926" -- in ink.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Lane Poole, Ruth, 1885-1974.
core
Advanced Science, EarlyView.This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu +10 more
wiley +1 more source
ASSESSMENT LANE CHANGING BEHAVIOR IN LOCAL RURAL ROADS
Journal of Engineering and Sustainable Development, 2019 The lane changing model is one of the most important cornerstone models to build a traffic microscopic simulation model. To build such lane changing model, there is a need to investigate the drivers’ characteristics from field data.
Ali Jihad Kadhim +1 more
doaj
Design for upholstered chair : sketch no. 7 [picture] /
, 1926 Part of collection: Furniture designs for Prime Minister's Lodge and Government House, Canberra.; Inscriptions: signed "Ruth Lane-Poole, 14/10/26" -- in ink.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Lane Poole, Ruth, 1885-1974.
core
Advanced Science, EarlyView.Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park +13 more
wiley +1 more source
Design for upholstered couch : sketch no. 84 [picture] /
, 1926 Part of collection: Furniture designs for Prime Minister's Lodge and Government House, Canberra.; Inscriptions: signed "Ruth Lane-Poole, Dec. 6. 1926" -- in ink.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Lane Poole, Ruth, 1885-1974.
core
Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins
Advanced Science, EarlyView.Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller +2 more
wiley +1 more source
Advanced Science, EarlyView.The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan +9 more
wiley +1 more source