Results 81 to 90 of about 9,638 (167)

Outcome of treatment with trametinib in adults with histiocytic neoplasms in the United Kingdom

British Journal of Haematology, Volume 209, Issue 2, Page 747-754, August 2026.
Trametinib (MEK inhibitor) shows efficacy in refractory and high‐risk adult histiocytic neoplasms. At a median follow‐up of 21.4 months, the clinical response rate was 81% (30/37) and the radiological response was 68% (25/37) (n = 37).
Rodothea Amerikanou, Talha Munir, Kristian Bowles, Christopher McNamara, Nikesh Chavda, Elizabeth Price, Jagdish Adiyodi, Alasdair Coles, Philippa Kelsey, Jeffery Smith, Richard Adams, Hayder Hussein, Rui Zhao, Trung Nguyen, Matthew Collin, Satyen Gohil   +15 more
wiley   +1 more source

A Rare Case of Cutaneous Crystal‐Storing Histiocytosis With Kappa Light Chain Restriction and Unusual BCL6 Expression

Journal of Cutaneous Pathology, Volume 53, Issue 8, Page 682-686, August 2026.
ABSTRACT Crystal‐storing histiocytosis (CSH) is a rare histopathologic phenomenon characterized by the accumulation of crystalline material within histiocytes, most often associated with lymphoplasmacytic or plasma cell neoplasms. Cutaneous involvement is uncommon and may present diagnostic challenges.
Liangli Wang, Jonathan L. Curry, Julia Dai, Daniel H. Wang, Paolo Strati, Melody R. Becnel, Leomar Y. Ballester, Carlos A. Torres‐Cabala, Phyu P. Aung   +8 more
wiley   +1 more source

Novel BRAF fusion in Erdheim–Chester disease with pulmonary manifestations: Importance of RNA‐based testing and response to MEK inhibition

Histopathology, Volume 89, Issue 3, Page 558-561, September 2026.
Igor Odintsov, Henry D. Tazelaar, Jerry C. Lee, Lloyd E. Damon, Walter Patrick Devine, Kirk D. Jones   +5 more
wiley   +1 more source

Langerhans Cell Histiocytosis of the Clavicle in a 13-Year-Old Boy

Case Reports in Orthopedics, 2014
Langerhans Cell Histiocytosis (LCH) is a rare neoplasm characterized by abnormal proliferation of histiocytic cells. In this case report, we describe a unique case of a 13-year-old boy who presented to the clinic with an insidious onset of mid-clavicular
Shital N. Parikh, Vishal R. Desai, Anita Gupta, Christopher G. Anton   +3 more
doaj   +1 more source

Intestinal Langerhans cell histiocytosis presenting with symptoms similar to inflammatory bowel disease: a case report

Pathology and Oncology Research
Background:Langerhans cell histiocytosis is a rare disease characterized by the abnormal proliferation of Langerhans cells within a single organ or multiple organs.
Yuqing Liu, Zhenwei Chen, Lu Wang, Baizhou Li   +3 more
doaj   +1 more source

Paediatric Langerhans cell histiocytosis with diabetes insipidus: remarkable recovery journey

Journal of the Pakistan Medical Association
A rare condition known as Langerhans cell histiocytosis (LCH) is characterised by the clonal growth of dendritic cells called Langerhans cells, which play a significant role in the immune system. A diverse range of clinical presentations are probable as
Versha Rani Rai, Zulqarnain Buriro, Roshia Parveen, Mohsina Noor, Heeranand Rathore   +4 more
doaj   +1 more source

Langerhans Cell Histiocytosis [PDF]

Ear, Nose & Throat Journal, 2010
Sandra, Camelo-Piragua, Eduardo, Zambrano, Liron, Pantanowitz   +2 more
openaire   +2 more sources

A case of diagnosis and treatment of mediastinal Langerhans cytosis

Journal of Cardiothoracic Surgery
Background Langerhans cell histiocytosis (LCH) is a rare disease. It mainly involves abnormal proliferation and aggregation of Langerhans cells, a type of cell of the immune system.Langerhans cytosis is more common in the bone, but it has rarely been ...
Yumeng Niu, Lei Xian, Yi Wang, Yourong Chen, Yifei Lu, Daying Liang   +5 more
doaj   +1 more source

Unusual Neurological Manifestation of Langerhans Cell Histiocytosis in an Adult

Ear, Nose & Throat Journal
Langerhans Cell Histiocytosis is a rare disorder characterized by an abnormal proliferation of Langerhans cells in one or multiple organs. It rarely presents with a central vestibular involvement.
Imen Achour MD, Ines Kharrat MD, Youssef Hbaieb MD, Mariam Ben Ayed MD, Malek Mnejja MD, Bouthaina Hammami MD, Basma Souissi MD, Ilhem Charfeddine MD   +7 more
doaj   +1 more source

Sonography of thyroid involvement in Langerhans cell histiocytosis. [PDF]

JCEM Case Rep
Yamashita Y, Sasai Y, Yamagami K, Kanamoto N.   +3 more
europepmc   +1 more source