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Langerhans‐Cell Histiocytosis [PDF]
Indian Journal of Medical Research, 2018 Langerhans cell histiocytosis (LCH) formerly known as pulmonary eosinophilic granuloma is currently regarded by the World Health Organization as a clonal neoplastic proliferation of histiocytes.
C. Allen, M. Merad, K. McClain
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Langerhans Cell histiocytosis. [PDF]
Blood, 2020 Langerhans Cell Histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction.
C. Rodríguez-Galindo, C. Allen
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Langerhans Cell Histiocytosis [PDF]
Dermatology Online Journal, 2002 Adult onset Langerhans cell histiocytosis is uncommon. A 29 year old man is presented who developed classic cutaneous disease with severe systemic involvement. He responded completely to a two month course of thalidomide.
Geraldine S. Pinkus +5 more
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Langerhans' cell histiocytosis in adults [PDF]
Journal of the American Academy of Dermatology, 1997 Three cases of Langerhans' cell histiocytosis with unusual clinical and histopathologic features are described. The first two cases illustrate diagnostic pitfalls that underscore the importance of considering Langerhans' cell histiocytosis in the differential diagnosis of purpuric papular eruptions of the scalp and intertriginous areas, particularly in
Fiorina Giona +9 more
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Langerhans cell histiocytosis [PDF]
British Journal of Haematology, 2000 Richard D. Brunning
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Differentiation of Langerhans cells in Langerhans cell histiocytosis
Blood, 2001 Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges from spontaneous resolution to a chronic and sometimes lethal disease. We studied 25 patients with various clinical forms of the disease.
Frédéric Geissmann +8 more
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Langerhans cell histiocytosis [PDF]
Sao Paulo Medical Journal, 1998 The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentine, but the diagnosis was done with the demonstration of Birbeck granules with ...
Chauffaille, Maria de Lourdes Lopes Ferrari UNIFESP +10 more
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Blood, 2022 Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary (smoking-associated), or multisystem disease.
G. Goyal +17 more
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Langerhans cell histiocytosis: Version 2021
Hematological Oncology, 2021 Children with Langerhnans cell histiocytosis (LCH) develop granulomatous lesions with characteristic clonal CD207+ dendritic cells that can arise as single lesions or life‐threatening disseminated disease. Despite the wide range of clinical presentations,
N. Gulati, C. Allen
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Update on Pulmonary Langerhans Cell Histiocytosis
Frontiers in Medicine, 2021 Pulmonary Langerhans cell (LC) histiocytosis (PLCH) has unknown cause and is a rare neoplastic disorder characterized by the infiltration of lungs and various organs by bone marrow-derived Langerhans cells with an accompanying strong inflammatory ...
E. Radzikowska
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