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Langerhans cell histiocytosis [PDF]

Sao Paulo Medical Journal, 1998
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations.
Atallah, Álvaro Nagib, Chauffaille, Maria de Lourdes Lopes Ferrari, Diniz, Cybelle Maria Costa, Enokihara, Silva, Ferreira, Karin Ventura, Hassun, Karine Marques, Kerbauy, José, Martinez, José Antônio Baddini, Michalany, Nylceo, Simões, Milvia Maria, Valério, Rosana M.   +10 more
core   +17 more sources

Langerhans‐Cell Histiocytosis [PDF]

Indian Journal of Medical Research, 2018
Langerhans cell histiocytosis (LCH) formerly known as pulmonary eosinophilic granuloma is currently regarded by the World Health Organization as a clonal neoplastic proliferation of histiocytes.
C. Allen, M. Merad, K. McClain
semanticscholar   +6 more sources

Langerhans Cell histiocytosis. [PDF]

Blood, 2020
Langerhans Cell Histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction.
C. Rodríguez-Galindo, C. Allen
semanticscholar   +4 more sources

Langerhans´cell histiocytosis [PDF]

Cancer Control, 2014
La histiocitosis de células de Langerhans (HCL), anteriormente conocida como histiocitosis X, es una enfermedad poco frecuente caracterizada por la acumulación y proliferación de histiocitos, eosinófilos y células de Langerhans, con inclusión de gránulos
Casanovas, A., Elena, G., Rosso, Diego
core   +9 more sources

Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis

Cell Communication and Signaling, 2022
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK
Xue-min Gao, Jian Li, Xin-xin Cao
doaj   +2 more sources

Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature

Journal of Medical Case Reports, 2021
Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
doaj   +2 more sources

Langerhans cell histiocytosis present in a 1-day-old girl: a case report [PDF]

Journal of Medical Case Reports
Background Langerhans cell histiocytosis is a rare condition characterized by diverse clinical manifestations, ranging from cutaneous lesions to systemic involvement.
Yang Meng
doaj   +2 more sources

Langerhans Cell Histiocytosis [PDF]

Dermatology Online Journal, 2002
Adult onset Langerhans cell histiocytosis is uncommon. A 29 year old man is presented who developed classic cutaneous disease with severe systemic involvement. He responded completely to a two month course of thalidomide.
Geraldine S. Pinkus, Mark A. Lones, Fumio Matsumura, Shigeko Yamashiro, Jonathan W. Said, Jack L. Pinkus   +5 more
openalex   +5 more sources

Langerhans cell histiocytosis on the penis: a case report [PDF]

BMC Urology, 2006
Background Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs.
Kuroda Isao, Ashimine Satoshi, Ueno Munehisa, Hagiuda Jun, Ishizawa Keisuke, Deguchi Nobuhiro   +5 more
doaj   +4 more sources

TERT Promoter C228T and C250T Hotspot Mutations Are Absent in BRAF V600E‐Positive Langerhans Cell Histiocytosis [PDF]

Cancer Med
ABSTRACT Background In various malignancies, the co‐occurrence of BRAF V600E and TERT promoter mutations (C228T and C250T) has been associated with tumor aggressiveness and poor prognosis. However, the presence of these TERT promoter mutations in Langerhans cell histiocytosis (LCH) remains unexplored.
Silva A, Hélias‐Rodzewicz Z, Ungureanu I, Emile J.   +3 more
europepmc   +2 more sources