Results 111 to 120 of about 100,070 (311)
Multisystem Langerhans cell histiocytosis coexisting with metastasizing adenocarcinoma of the lung: A case report [PDF]
, 2013 Introduction. Langerhans cell histiocytosis (LCH) is an uncommon disease of unknown etiology characterized by uncontrolled proliferation and infiltration of various organs by Langerhans cells. Case report. We presented a 54-year-old man, heavy smoker,
Eri Živka +6 more
core +1 more source
Clinical and Translational Science, Volume 18, Issue 5, May 2025.ABSTRACT Pharmacogenomics remains underutilized in pediatric oncology, despite the existence of evidence‐based guidelines. Implementation of pharmacogenomics‐informed prescribing could improve medication safety and efficacy in pediatric oncology patients, who are at high risk of adverse drug reactions.
Claire Moore +8 more
wiley +1 more source
Self-assembly, Buckling & Density-Invariant Growth of Three-dimensional Vascular Networks [PDF]
arXiv, 2019 The experimental actualisation of organoids modelling organs from brains to pancreases has revealed that much of the diverse morphologies of organs are emergent properties of simple intercellular "rules" and not the result of top-down orchestration. In contrast to other organs, the initial plexus of the vascular system is formed by aggregation of cells
arxiv
Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults.
Blood, 2017 Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) are rare histiocytic disorders induced by somatic mutation of MAPK pathway genes. BRAFV600E mutation is the most common mutation in both conditions and also occurs in the hematopoietic
Paul Milne +16 more
semanticscholar +1 more source
Pulmonary Langerhans cell histiocytosis [PDF]
European Journal of Pediatrics, 2013 Herein, we described 16-year-old boy with pulmonary cysts in both lung fields and diagnosed as isolated pulmonary Langerhans cell histiocytosis.
ÖZDEMİR, Mehmet Akif, KÖSE, Mehmet
openaire +4 more sources
ACR Open Rheumatology, Volume 7, Issue 4, April 2025.A middle‐aged woman presented with a granulomatous breast lesion in 2018. By 2021, antibiotic‐resistant pneumonia led to the discovery of granulomatous inflammation in the lung and thyroid. Initially misdiagnosed as Erdheim–Chester disease (ECD), she was treated with interferon without success.
Benedetta Fazzi +4 more
wiley +1 more source
Bagaimana Prognosis Histiocytosis? Sebuah Laporan Kasus [PDF]
, 2013 Penderita histiocytosis dengan keterlibatan multiorgan dan disertai gangguan fungsi organ mempunyai prognosis buruk dan tingkat mortalitas tinggi. Dilaporkan seorang penderita histiocytosis, usia 1 tahun 1 bulan yang datang dengan kelainan di kulit ...
Lestari, R. D. (Rini) +1 more
core
New somatic BRAF splicing mutation in Langerhans cell histiocytosis
Molecular Cancer, 2017 Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with constitutive activation of the MAPKinase RAS-RAF-MEK-ERK cell signaling pathway. We analyzed 9 LCH cases without BRAF V600 and MAP2K1 mutations by whole exome sequencing.
Sébastien Héritier +10 more
doaj +1 more source
Langerhans cell histiocytosis: current concepts in dentistry and case report [PDF]
, 2016 Langerhans cell histiocytosis (LCH), which is a rare granulomatous pediatric disease of unknown etiology, is characterized by the idiopathic proliferation and accumulation of abnormal and clonal Langerhans cells or their ...
Alejo-Gonzalez, Francisco +4 more
core
Cancer Medicine, 2018 Langerhans cell histiocytosis (LCH) is a rare disorder of histiocyte proliferation. Previous case studies suggest a higher prevalence of hematologic and solid malignancies among LCH patients, possibly due to treatment with tumorigenic agents such as ...
Jennifer Ma +5 more
semanticscholar +1 more source