Results 11 to 20 of about 15,157 (219)

Beyond Hepatitis: A Rare Case of Multisystem Langerhans Cell Histiocytosis in a Child. [PDF]

Clin Case Rep
ABSTRACT Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder involving abnormal proliferation of dendritic cells, with clinical presentations ranging from isolated lesions to life‐threatening multisystem involvement. This case report describes a 26‐month‐old girl who presented with progressive jaundice, fever, hepatomegaly, pruritic scalp
Neupane D, Banjade RR, Joshi D, Awasthi PR, Mishra S.   +4 more
europepmc   +2 more sources

Adult Langerhans cell histiocytosis presenting with multisystem involvement and sarcomatoid features: a case report

Journal of Medical Case Reports, 2020
Background Langerhans cell tumors are rare clonal disorders characterized by neoplastic proliferation of dendritic cells that can be further classified into the subtypes Langerhans cell histiocytosis and Langerhans cell sarcoma, which are rare neoplasms ...
Luis E. Aguirre, Ingrid Schwartz, Jennifer Chapman, Marcelo F. Larsen, Alvaro Alencar   +4 more
doaj   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature

Journal of Medical Case Reports, 2021
Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
doaj   +1 more source

Langerhans cell histiocytosis [PDF]

Blood, 2020
Abstract Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction. The pathogenic cells are defined by constitutive activation of the MAPK signaling pathway.
Carl E. Allen, Carlos Rodriguez-Galindo
openaire   +3 more sources

Primary Langerhans Cell Histiocytosis of the Extrahepatic Bile Duct Occurring in an Adult Patient

Balkan Medical Journal, 2018
Background: Langerhans cell histiocytosis is characterized by an abnormal proliferation of neoplastic Langerhans cells. Langerhans cell histiocytosis commonly affects the pediatric population, whereas presentation in adults remains a rare event.
Ifeyinwa E. Obiorah, Alicia Henao Velasquez, Bhaskar Kallakury, Metin Özdemirli   +3 more
doaj   +1 more source

Langerhans cell histiocytosis

Journal of Indian Society of Periodontology, 2011
Langerhans cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosa.
Sushma Galgali, G Pushpalatha, Prashanthy, D R Aruna   +3 more
openaire   +3 more sources

Langerhans cell histiocytosis on the penis: a case report

BMC Urology, 2006
Background Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs.
Kuroda Isao, Ashimine Satoshi, Ueno Munehisa, Hagiuda Jun, Ishizawa Keisuke, Deguchi Nobuhiro   +5 more
doaj   +1 more source

Langerhans Cell Histiocytosis with Extensive Spinal and Thyroid Gland Involvement Presenting with Quadriparesis: An Unusual Case in an Adult Patient [PDF]

Malaysian Orthopaedic Journal, 2011
Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit. Involvement of thyroid tissue is also rare, even in multifocal disease presentations.
Mohd Ariff S, Joehaimey J, Ahmad Sabri O, Zulmi W   +3 more
doaj   +1 more source

Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study

Orphanet Journal of Rare Diseases, 2020
Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe presentations are observed. Methods Among 1482 children (
Solenne Le Louet, Mohamed-Aziz Barkaoui, Jean Miron, Claire Galambrun, Nathalie Aladjidi, Pascal Chastagner, Kamila Kebaili, Corinne Armari-Alla, Anne Lambilliotte, Julien Lejeune, Despina Moshous, Valeria Della Valle, Chiara Sileo, Hubert Ducou Le Pointe, Jean-François Chateil, Sylvain Renolleau, Jean-Eudes Piloquet, Aurelie Portefaix, Ralph Epaud, Raphaël Chiron, Emmanuelle Bugnet, Gwenaël Lorillon, Abdelatif Tazi, Jean-François Emile, Jean Donadieu, Sébastien Héritier   +25 more
doaj   +1 more source