Results 11 to 20 of about 51,953 (228)

Langerhans Cell Histiocytosis [PDF]

open access: yesSurvey of Ophthalmology, 2008
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia characterized by accumulation of clonal CD1a-positive immature dendritic cells (LCH cells) accompanied by infiltration of various inflammatory cells such as eosinophils, lymphocytes, macrophages, and osteoclast-like multinuclear giant cells.
Department of Ophthalmology and Pathology, University of South Florida, College of Medicine, and Section of Ophthalmology James A. Haley Veterans Hospital, Tampa, Florida, USA ( host institution )   +2 more
core   +8 more sources

Hepatic Langerhans cell histiocytosis: A review

open access: yesWorld Journal of Clinical Oncology, 2021
Hepatic Langerhans cell histiocytosis (LCH) is characterized by proliferation and accumulation of Langerhans cells in the liver, causing liver dysfunction or forming a mass lesion.
Zhiyan Fu   +4 more
semanticscholar   +1 more source

Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2021
Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms.
M. Hamdan, J. Qiao, Vid Fikfak
semanticscholar   +1 more source

Radiotherapy in langerhans cell histiocytosis : a rare indication in a rare disease [PDF]

open access: yes, 2013
Introduction: Langerhans Cell Histiocytosis (LCH) represents a rare benign disorder, previously designated as "Histiocytosis X", "Type II Histiocytosis" or "Langerhans Cell Granulomatosis".
Bruns, Frank   +8 more
core   +3 more sources

Langerhans cell histiocytosis

open access: yesJournal of Indian Society of Periodontology, 2011
Langerhans cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosa.
Sushma Galgali   +3 more
openaire   +3 more sources

Efficacy of BRAF-inhibitor therapy in BRAFV600E -mutated Adult Langerhans Cell Histiocytosis.

open access: yesThe Oncologist, 2020
Langerhans-cell histiocytosis (LCH) is a rare disease of unknown pathogenesis. To date, there is a lack of FDA-approved treatments in adult LCH to establish optimal first line therapy.
A. Hazim   +15 more
semanticscholar   +1 more source

Langerhans cell histiocytosis on the penis: a case report [PDF]

open access: yes, 2006
BACKGROUND: Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs.
A Singh   +15 more
core   +3 more sources

Langerhans Cell Histiocytosis [PDF]

open access: yesCancer Control, 2014
Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
Scott Kelly, Michael T. Yen
openaire   +5 more sources

CSF1R Is Required for Differentiation and Migration of Langerhans Cells and Langerhans Cell Histiocytosis

open access: yesCancer immunology research, 2020
CSF1R promotes efficient Langerhans cell (LC) differentiation from hematopoietic progenitors and migration, which may be reduced by CSF1R kinase inhibition.
S. Lonardi   +15 more
semanticscholar   +1 more source

Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: A case report [PDF]

open access: yes, 2012
INTRODUCTION: Langerhans cell histiocytosis is a rare disease within the adult population, with very few cases reported as solitary hypophyseal lesions in adults.
Chicoine, Michael R   +8 more
core   +2 more sources

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