Results 31 to 40 of about 99,409 (309)
Langerhans cell histiocytosis of liver [PDF]
, 2020 Langerhans cell histiocytosis (LCH) is a rare disorder of unknown etiology caused by proliferation of Langerhans cells. It can involve single organ system to multi organ systems and clinical presentation is variable depending on the organ involved and ...
Duvuru, Nageshwar Reddy +3 more
core +2 more sources
Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study
Orphanet Journal of Rare Diseases, 2020 Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe presentations are observed. Methods Among 1482 children (
Solenne Le Louet +25 more
doaj +1 more source
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis
Cell Communication and Signaling, 2022 Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK
Xue-min Gao, Jian Li, Xin-xin Cao
doaj +1 more source
Efficacy of BRAF-inhibitor therapy in BRAFV600E -mutated Adult Langerhans Cell Histiocytosis.
The Oncologist, 2020 Langerhans-cell histiocytosis (LCH) is a rare disease of unknown pathogenesis. To date, there is a lack of FDA-approved treatments in adult LCH to establish optimal first line therapy.
A. Hazim +15 more
semanticscholar +1 more source
Solitary Langerhans cell histiocytosis of liver with sclerosing cholangitis in an adult female [PDF]
, 2017 Liver is affected as a late complication of high risk cases of Langerhans cell histiocytosis. Sclerosing cholangitis is a rare pattern associated with Langerhans cell histiocytosis of liver, which is even rarer in the adult population and has high ...
Kader, Nazneen A. +2 more
core +2 more sources
Langerhans Cell Histiocytosis [PDF]
Cancer Control, 2014 Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
Scott Kelly, Michael T. Yen
openaire +5 more sources
Cancer immunology research, 2020 CSF1R promotes efficient Langerhans cell (LC) differentiation from hematopoietic progenitors and migration, which may be reduced by CSF1R kinase inhibition.
S. Lonardi +15 more
semanticscholar +1 more source
Enhanced mechanical heterogeneity of cell collectives due to temporal fluctuations in cell elasticity [PDF]
Phys. Rev. E 107, 014401 (2023), 2022 Cells are dynamic systems characterized by temporal variations in biophysical properties such as stiffness and contractility. Recent studies show that the recruitment and release of actin filaments into and out of the cell cortex - a network of proteins underneath the cell membrane - leads to cell stiffening prior to division and softening immediately ...
arxiv +1 more source
Haematologica, 2008 Clinical features, brain magnetic resonance imaging findings and EDSS scores of 11 patients with neurodegenerative central nervous system Langerhans cell histiocytosis were analyzed in Japan.
Shinsaku Imashuku +13 more
doaj +1 more source
Journal of Contemporary Medicine, 2022 Scabies is an infestation caused by the Sarcoptes scabiei burrowing into the epidermis. Histopathologically scabies infestation may reveal Langerhans cell hyperplasia which might cause misdiagnosis of Langerhans cell histiocytosis in some cases.
Ayşe Esra Koku Aksu +5 more
doaj +1 more source