BRAFV600E mutation in cutaneous lesions of patients with adult Langerhans cell histiocytosis. [PDF]
, 2015 BACKGROUND: Langerhans cell histiocytosis (LCH) is characterized by the proliferation of pathologic Langerhans cells. The disease can develop in any age and can affect almost any organ. Cutaneous involvement is frequent in LCH.
Badalian-Very +18 more
core +4 more sources
Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation
JEADV Clinical Practice, 2022 Congenital self‐healing Langerhans cell histiocytosis (CSHLCH) is a rare variant of Langerhans cell histiocytosis characterised by the presence of skin lesions in the neonate and spontaneous self‐healing after a variable period of time.
Mar Ramírez‐Lluch +7 more
doaj +1 more source
Langerhans Cell Histiocytosis: An Unusual Presentation
Philippine Journal of Otolaryngology Head and Neck Surgery, 2008 Objective: To describe an unusual presentation of Langerhans cell histiocytosis in the craniofacial skeleton in a patient previously diagnosed with Pott’s disease. Methods: Design: Case report. Setting: Tertiary care center. Patient: One
Kathleen R. Fellizar +1 more
doaj +1 more source
A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult
Proceedings of Singapore Healthcare, 2011 Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
doaj +1 more source
A Case of Orbital Langerhans Cell Histiocytosis in an Adult
Acta Médica Portuguesa, 2019 Langerhans cell histiocytosis remains an enigmatic disease with a very heterogeneous presentation. We describe a rare case of orbital Langerhans cell histiocytosis in a 39-year-old female patient who presented right orbital pain and edema of the upper ...
Inês Carneiro +2 more
doaj +1 more source
Isolated Langerhans Histiocytosis in Thyroid: Thyroidectomy or Chemotherapy? [PDF]
Journal of Clinical and Diagnostic Research, 2015 Langerhans cell histiocytosis (LCH) is a rare disorder of mononuclear phagocytic system whose clinical presentation varies from the localised involvement of a single bone to a widely disseminated disease.
Anoop Attakkil +4 more
doaj +1 more source
Effective BRAF inhibitor vemurafenib therapy in a 2-year-old patient with sequentially diagnosed Langerhans cell histocytosis and Erdheim-Chester disease [PDF]
, 2017 Erdheim–Chester disease (ECD) is a rare histiocytic disorder, characterized by the xanthomatous infiltration of tissues by CD68-positive and CD1a-/CD100-negative foamy histiocytes. In childhood, ECD is exceptionally rare, and only a dozen cases have been
Bánusz, Rita +6 more
core +2 more sources
Clinical Case Reports, 2023 Key Clinical Message Pulmonary Langerhans cell histiocytosis should be evaluated even in adults with no previous medical history and no history of cigarette smoking who have spontaneous pneumothorax and evidence of multiple lung cystic lesions, and other
Mitra Samareh Fekri +3 more
doaj +1 more source
BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate [PDF]
, 2013 Hemorrhagic pustules with a “blueberry muffin” appearance accompanied by respiratory failure in a neonate present a challenging differential diagnosis that includes infections and neoplasms.
Aslam, Muhammad +8 more
core +3 more sources
Gastrointestinal Tract Involvement of Langerhans Cell Histiocytosis: Concerning Point of Diagnosis
Journal of Health Science and Medical Research (JHSMR), 2020 An 8-month-old girl presented with chronic mucous bloody diarrhea for 3 months. She was diagnosed as infective gastroenteritis and did not improve after antibiotic treatment.
Shevachut Chavananon +2 more
doaj +1 more source