Results 41 to 50 of about 24,465 (270)

Effective BRAF inhibitor vemurafenib therapy in a 2-year-old patient with sequentially diagnosed Langerhans cell histocytosis and Erdheim-Chester disease [PDF]

, 2017
Erdheim–Chester disease (ECD) is a rare histiocytic disorder, characterized by the xanthomatous infiltration of tissues by CD68-positive and CD1a-/CD100-negative foamy histiocytes. In childhood, ECD is exceptionally rare, and only a dozen cases have been
Bánusz, Rita, Csomor, Judit, Csóka, Monika, Kertész, Gabriella, Krisztián Kállay, Varga, Edit, Váradi, Zsófia   +6 more
core   +2 more sources

Langerhans cell histiocytosis of the maxillae in a child treated only with chemotherapy: a case report

Journal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a sporadic disease caused by an uncontrolled pathogenic clonal proliferation of dendritic cells that have Langerhans cell characteristics.
Angela Pia Cazzolla, Giuseppe Troiano, Khrystyna Zhurakivska, Eugenio Maiorano, Gianfranco Favia, Maria Grazia Lacaita, Giuseppe Marzo, Franca Dicuonzo, Stefano Andresciani, Lorenzo Lo Muzio   +9 more
doaj   +1 more source

Gastrointestinal Tract Involvement of Langerhans Cell Histiocytosis: Concerning Point of Diagnosis

Journal of Health Science and Medical Research (JHSMR), 2020
An 8-month-old girl presented with chronic mucous bloody diarrhea for 3 months. She was diagnosed as infective gastroenteritis and did not improve after antibiotic treatment.
Shevachut Chavananon, Pornpun Sripornsawan, Thirachit Chotsampancharoen   +2 more
doaj   +1 more source

An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]

, 2016
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey, Betts, Alexandra, Boffa, Michael J., Gatt, Alex   +3 more
core  

Clinical quiz. [PDF]

, 2005
J Pediatr Gastroenterol Nutr. 2005 Oct;41(4):483-4, 484. Clinical quiz. Prior AC, Selores M, Pina R, Dias JA, Costa FM, Vale L, Gomes L. Department of Pediatrics, Hospital Geral de Santo António, Portugal.
COSTA, F.M., DIAS, J.A., GOMES, L., PINA, R., PRIOR, A.C., SELORES, M., VALE, L.   +6 more
core   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues. [PDF]

, 2014
International audienceBACKGROUND: Langerhans cell (LC) sarcoma (LCS) is a high-grade neoplasm with overtly malignant cytologic features and an LC phenotype.
A Kanik, A Kubo, C Pancaldi, CET da Costa, D Schrama, D Tortorella, DP O'Malley, E Izmailova, Francis Jaubert, H Feng, Hirokazu Nakamine, I Grosjean, I Murakami, Ichiro Murakami, J Banchereau, J Engelmayer, Jean Gogusev, Katsuyoshi Takata, Kazuhiko Hayashi, KD Mertz, KJ Busam, M Matsushita, M Shamoto, M Shuda, Masako Kato, Michiko Matsushita, Mitsunori Yamakawa, R Jaffe, S Kuwamoto, S Kuwamoto, S Weitzman, Satoshi Kuwamoto, Shu Nakamoto, Tadashi Yoshino, Takashi Oka, Takeshi Iwasaki, X Sastre-Garau, Yasushi Horie, YL Tolstov   +38 more
core   +4 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Multisystem Langerhans cell histiocytosis coexisting with metastasizing adenocarcinoma of the lung: A case report [PDF]

, 2013
Introduction. Langerhans cell histiocytosis (LCH) is an uncommon disease of unknown etiology characterized by uncontrolled proliferation and infiltration of various organs by Langerhans cells. Case report. We presented a 54-year-old man, heavy smoker,
Eri Živka, Klem Ištvan, Lovrenski Aleksandra, Panjković Milana, Považan Đorđe, Tegeltija Dragana, Đurić Mirna   +6 more
core   +1 more source

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source