Results 41 to 50 of about 99,409 (309)

Langerhans cell histiocytosis

open access: yesJournal of Indian Society of Periodontology, 2011
Langerhans cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosa.
Sushma Galgali   +3 more
openaire   +3 more sources

Pulmonary Langerhans cell histiocytosis causing spontaneous bilateral pneumothorax in a child

open access: yesThe Egyptian Journal of Internal Medicine, 2015
Bilateral pneumothorax is very rare in childhood. Moreover, if it is due to pulmonary involvement of Langerhans cell histiocytosis, it is even rarer in childhood.
Anupam Patra   +3 more
doaj   +1 more source

Swelling of bilateral parotid glands: An unusual symptom of multisystem Langerhans cell histiocytosis

open access: yesSAGE Open Medical Case Reports, 2014
Objective: Langerhans cell histiocytosis is an unusual disorder of unknown etiology with heterogeneous clinical behaviors and variable outcomes. It can involve one or more organs or systems, but to our best knowledge, parotid glands involvement in ...
Xiaojun Yuan   +4 more
doaj   +1 more source

Vemurafenib for Refractory Multisystem Langerhans Cell Histiocytosis in Children: An International Observational Study

open access: yesJournal of Clinical Oncology, 2019
PURPOSE Off-label use of vemurafenib (VMF) to treat BRAFV600E mutation–positive, refractory, childhood Langerhans cell histiocytosis (LCH) was evaluated. PATIENTS AND METHODS Fifty-four patients from 12 countries took VMF 20 mg/kg/d. They were classified
J. Donadieu   +45 more
semanticscholar   +1 more source

Langerhans cell sarcoma of the skin in association with superficial atypical Langerhans cell proliferation

open access: yesRare Tumors, 2017
Langerhans cell sarcoma of the skin is a rare tumor with aggressive behavior. There are reports of Langerhans cell sarcoma involving the skin in patients with underlying systemic Langerhans cell histiocytosis.
Alejandro Peralta Soler   +2 more
doaj   +1 more source

Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation

open access: yesJEADV Clinical Practice, 2022
Congenital self‐healing Langerhans cell histiocytosis (CSHLCH) is a rare variant of Langerhans cell histiocytosis characterised by the presence of skin lesions in the neonate and spontaneous self‐healing after a variable period of time.
Mar Ramírez‐Lluch   +7 more
doaj   +1 more source

Shaping bursting by electrical coupling and noise [PDF]

open access: yesBiological Cybernetics Volume 106, Number 2 (2012), 67-88, 2011
Gap-junctional coupling is an important way of communication between neurons and other excitable cells. Strong electrical coupling synchronizes activity across cell ensembles. Surprisingly, in the presence of noise synchronous oscillations generated by an electrically coupled network may differ qualitatively from the oscillations produced by uncoupled ...
arxiv   +1 more source

Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: A case report [PDF]

open access: yes, 2012
INTRODUCTION: Langerhans cell histiocytosis is a rare disease within the adult population, with very few cases reported as solitary hypophyseal lesions in adults.
Chicoine, Michael R   +8 more
core   +2 more sources

Learning theories reveal loss of pancreatic electrical connectivity in diabetes as an adaptive response [PDF]

open access: yesPLoS ONE 8(8): e70366 (2013), 2013
Cells of almost all solid tissues are connected with gap junctions which permit the direct transfer of ions and small molecules, integral to regulating coordinated function in the tissue. The pancreatic islets of Langerhans are responsible for secreting the hormone insulin in response to glucose stimulation.
arxiv   +1 more source

The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on $\textrm{Ca}^{2+}$ dynamics [PDF]

open access: yes, 2020
Type 2 diabetes (T2D) is a challenging metabolic disorder characterized by a substantial loss of $\beta$-cell mass and alteration of $\beta$-cell function in the islets of Langerhans, disrupting insulin secretion and glucose homeostasis. The mechanisms for deficiency in $\beta$-cell mass and function during the hyperglycemia development and T2D ...
arxiv   +1 more source

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