Pulmonary langerhans cell histiocytosis [PDF]
Orphanet Journal of Rare Diseases, 2012 AbstractPulmonary Langerhans Cell Histiocytosis (PLCH) is a relatively uncommon lung disease that generally, but not invariably, occurs in cigarette smokers. The pathologic hallmark of PLCH is the accumulation of Langerhans and other inflammatory cells in small airways, resulting in the formation of nodular inflammatory lesions.
Harpreet S. Suri +3 more
openaire +4 more sources
BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate [PDF]
, 2013 Hemorrhagic pustules with a “blueberry muffin” appearance accompanied by respiratory failure in a neonate present a challenging differential diagnosis that includes infections and neoplasms.
Aslam, Muhammad +8 more
core +3 more sources
High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.
Blood, 2017 Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis that most commonly affects adults and is driven by a high frequency of mutations in BRAF, MAP2K1, and kinases promoting MAPK signaling.
M. Papo +22 more
semanticscholar +1 more source
Effective BRAF inhibitor vemurafenib therapy in a 2-year-old patient with sequentially diagnosed Langerhans cell histocytosis and Erdheim-Chester disease [PDF]
, 2017 Erdheim–Chester disease (ECD) is a rare histiocytic disorder, characterized by the xanthomatous infiltration of tissues by CD68-positive and CD1a-/CD100-negative foamy histiocytes. In childhood, ECD is exceptionally rare, and only a dozen cases have been
Bánusz, Rita +6 more
core +2 more sources
BMC Cancer, 2019 Langerhans cell histiocytosis (LCH) is a rare clonal disease, characterized by hyperproliferation of Langerhans cells. It may rarely involve the thyroid gland.
Mohammad A. Al Hamad +5 more
semanticscholar +1 more source
Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults.
Blood, 2017 Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) are rare histiocytic disorders induced by somatic mutation of MAPK pathway genes. BRAFV600E mutation is the most common mutation in both conditions and also occurs in the hematopoietic
Paul Milne +16 more
semanticscholar +1 more source
Choroidal Neovascular Membrane Formation and Retinochoroidopathy in a Patient with Systemic Langerhans Cell Histiocytosis: A Case Report and Review of the Literature [PDF]
, 2012 We report a case of bilateral atrophic retinochoroidopathy with choroidal neovascular membrane (CNVM) formation in a patient with systemic Langerhans cell histiocytosis (LCH).
Foster, Charles Stephen +3 more
core +2 more sources
Isolated Langerhans cell histiocytosis of the vulva: a case report and review of the literature [PDF]
, 2018 Isolated Langerhans cell histiocytosis (LCH) of the female genital tract is very rare. A review of the literature revealed that only 15 cases of primary vulvar LCH have previously been published in the English literature.
Beer, Karl +5 more
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Cancer Medicine, 2018 Langerhans cell histiocytosis (LCH) is a rare disorder of histiocyte proliferation. Previous case studies suggest a higher prevalence of hematologic and solid malignancies among LCH patients, possibly due to treatment with tumorigenic agents such as ...
Jennifer Ma +5 more
semanticscholar +1 more source
Langerhans cell histiocytosis: current concepts in dentistry and case report [PDF]
, 2016 Langerhans cell histiocytosis (LCH), which is a rare granulomatous pediatric disease of unknown etiology, is characterized by the idiopathic proliferation and accumulation of abnormal and clonal Langerhans cells or their ...
Alejo-Gonzalez, Francisco +4 more
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