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Clonal proliferation of Langerhans cells in Langerhans cell histiocytosis
The Lancet, 1994X-chromosome-inactivation assays can be used to assess clonality. We used such an assay at the human androgen-receptor gene locus in three female patients with histologically proven Langerhans cell histiocytosis. All patients were heterozygous for this locus.
R C, Yu, C, Chu, L, Buluwela, A C, Chu
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New England Journal of Medicine, 1987
Nearly a century has passed since Alfred Hand reported a case of "polyuria and tuberculosis,"1 later considered to be the first case of the Hand-Schul1er–Christian syndrome.
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Nearly a century has passed since Alfred Hand reported a case of "polyuria and tuberculosis,"1 later considered to be the first case of the Hand-Schul1er–Christian syndrome.
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Biology of Langerhans Cells and Langerhans Cell Histiocytosis
2006Langerhans cells (LC) are epidermal dendritic cells (DC). They play an important role in the initiation of immune responses through antigen uptake, processing, and presentation to T cells. Langerhans cell histiocytosis (LCH) is a rare disease in which accumulation of cells with LC characteristics (LCH cells) occur. LCH lesions are further characterized
G I, Bechan, R M, Egeler, R J, Arceci
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Pulmonary Langerhans’ cell histiocytosis
2007Pulmonary Langerhans’ cell histiocytosis (PLCH) is a diffuse, smoking-related lung disease characterized pathologically by bronchiolocentric inflammation, cyst formation, widespread vascular ...
Harari S., Caminati A.
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