Results 41 to 50 of about 16,328 (286)

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann   +25 more
wiley   +1 more source

Numerical simulation of the fractional Langevin equation

open access: yes, 2012
In this paper, we study the fractional Langevin equation, whose derivative is in Caputo sense. By using the derived numerical algorithm, we obtain the displacement and the mean square displacement which describe the dynamic behaviors of the fractional ...
Li, Changpin   +5 more
core   +1 more source

Generalized Langevin equation and the fluctuation-dissipation theorem for particle-bath systems in a harmonic field

open access: yesResults in Physics, 2019
The generalized Langevin equation (GLE) is extended to the case when not only the tagged particle but also the surrounding bath particles respond to the external harmonic potential K(x).
Vladimír Lisý, Jana Tóthová
doaj   +1 more source

Existence and stability analysis for Caputo generalized hybrid Langevin differential systems involving three-point boundary conditions

open access: yesBoundary Value Problems, 2023
This research inscription gets to grips with two novel varieties of boundary value problems. One of them is a hybrid Langevin fractional differential equation, whilst the other is a coupled system of hybrid Langevin differential equation encapsuling a ...
A. Boutiara   +3 more
doaj   +1 more source

On the Link between the Langevin Equation and the Coagulation Kernels of Suspended Nanoparticles

open access: yesFractal and Fractional, 2022
The ability of the Langevin equation to predict coagulation kernels in the transition regime (ranging from ballistic to diffusive) is not commonly discussed in the literature, and previous numerical works are lacking a theoretical justification.
José Morán
doaj   +1 more source

The Langevin equation

open access: yesComptes Rendus. Physique, 2017
The existence of atoms has been long predicted by philosophers and scientists. The development of thermodynamics and of the statistical interpretation of its concepts at the end of the nineteenth century and in the early years of the twentieth century made it possible to bridge the gap of scales between the macroscopic world and the world of atoms ...
Piasecki, Jarosław, Pomeau, Yves
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

An Analysis of Vehicular Traffic Flow Using Langevin Equation

open access: yesPromet (Zagreb), 2015
Traffic flow data are stochastic in nature, and an abundance of literature exists thereof. One way to express stochastic data is the Langevin equation. Langevin equation consists of two parts.
Çağlar Koşun   +2 more
doaj   +1 more source

Fast stochastic simulation of biochemical reaction systems by\ud alternative formulations of the Chemical Langevin Equation

open access: yes, 2010
The Chemical Langevin Equation (CLE), which is a stochastic differential equation (SDE) driven by a multidimensional Wiener process, acts as a bridge between the discrete Stochastic Simulation Algorithm and the deterministic reaction rate equation when ...
Etheridge, Alison M   +11 more
core   +1 more source

Triple Junctions as Dislocation‐Like Defects: The Role of Grain Boundary Crystallography Revealed by Experiment and Atomistic Simulation

open access: yesAdvanced Engineering Materials, EarlyView.
Grain boundary triple junctions are an essential ingredient of the microstructure of polycrystalline materials. In this study, a triple junction is observed using atomic‐resolution scanning transmission electron microscopy and characterized. Computer simulations reveal that the junction has a dislocation character that is determined by the joining ...
Tobias Brink   +4 more
wiley   +1 more source

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