Results 61 to 70 of about 3,505,641 (289)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Resisting rhetorics of language endangerment: Reclamation through Indigenous language survivance
Language Documentation and Description, 2017 Hill (2002) (and the robust discussions it inspired) demonstrated the importance of looking carefully at the rhetorics used by academics when discussing Indigenous and endangered languages. Fifteen years later this still remains a subject of concern.
doaj +2 more sources
Reo Ra’ivavae (Ra’ivavae, Austral Archipelago, French-occupied Polynesia) - Language Snapshot
Language Documentation and Description, 2021 Reo Ra’ivavae is the autochthonous language of the people of Ra’ivavae, in the Austral Islands of French-occupied Polynesia. It is also spoken in the administrative centre of French-occupied Polynesia, Tahiti, by the Ra’ivavae diaspora. Historically, the
doaj +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 2019 Sign languages of Papua New Guinea (PNG) are currently underreported and underdocumented. Yet, like many spoken languages of this region, these languages are highly likely to be endangered.
Rarrick, Samantha
core
The Ruthenian language in Serbia from the perspective of endangerment [PDF]
BalcanicaThe paper explores the endangerment of the Ruthenian language in Serbia through a mixed-method approach, combining quantitative and qualitative analyses of data obtained from a sociolinguistic questionnaire (VLingS Questionnaire 1.0; Mirić et al.
Paunović-Rodić Stefana
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Language Endangerment and Preservation in South Asia
, 2014 When it comes to language, few corners of the globe are as diverse as South Asia. Throughout history, this has been an area of high multilingualism and intense linguistic contact, leading to often extreme processes of change, linguistic conflict and ...
Cardoso, Hugo C.
core +2 more sources
Responses to Language Endangerment [PDF]
, 2013 This volume further complicates and advances the contemporary perspective on language endangerment by examining the outcomes of the most commonly cited responses to language endangerment, i.e. language documentation, language revitalization, and training.
Mihas, Elena +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source