Results 101 to 110 of about 85,242 (260)
Trudne miejsca w nauczaniu wymowy polskiej w środowisku bułgarskojęzycznym
Postscriptum Polonistyczne, 2020 The article deals with phonetic mistakes made by the students of Polish at The University of Veliko Turnovo (Bulgaria). The research covers over 50 students who studied Polish in 2008–2012, with the main focus on the recurrent mistakes and their sources.
Wirginia Mirosławska
doaj
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Opera slavica, 2014 The paper deals with the problem of teaching two South Slavonic languages to students whose mother tongue is also Slavonic – Czech or Slovak. In this complicated psycholinguistical situation we try to find the typical mistakes made because of ...
Elena Krejčová
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Language interference and interference mistakes in foreign language learning
The Humanities and Social Sciences, 2022 openaire +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
THE IMPORTANCE OF INTERFERENCE IN LANGUAGE ACQUISATION
This article explores the nuanced role of interference in language acquisition, shedding light on its significance in shaping the learning process. Interference, both positive and negative, manifests as the influence of a learner’s native language on the acquisition of a new language.
Hayitboeva, Diana Bahtiyor kizi +1 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source