Results 181 to 190 of about 408,491 (314)

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, EarlyView.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source

Navigating challenges in healthcare education: perspectives from ethnic minority students. [PDF]

BMC Med Educ
Wong MFF, Dhaliwal JKJ.
europepmc   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Intersectionality of cancer disparities in south Asia. [PDF]

Lancet Glob Health
Menon TP, Mathew A, Iyengar P, Gyawali B, Pramesh CS, Dee EC.   +5 more
europepmc   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Mixed-methods, participatory action research study exploring palliative and end-of-life care for LGBTIQ+ people in Switzerland: a protocol for the TRUST-PALL study. [PDF]

BMJ Open
Deml MJ, Meier C, Letras C, Canova N, Martinelli P, Jones L, Colussi G, Larkin PJ, Eisner L, Hässler T, Bosisio F, Gamondi C.   +11 more
europepmc   +1 more source

Utilizing Cooperative Proton–Electron Mixed Conduction Induced via Chemical Dedoping of Self‐Doped Poly(3,4‐ethylenedioxythiophene) Nanofilms for In‐Material Physical Reservoirs

Advanced Science, EarlyView.
This study demonstrates a new concept for high‐performance in‐material physical reservoirs (PRs). An intrinsic and cooperative ion–electron state, induced by chemical dedoping in self‐doped poly(3,4‐ethylenedioxythiophene) (S‐PEDOT) nanofilms, enhances the performance of in‐material PRs.
Yuya Ishizaki‐Betchaku, Motoaki Onishi, Tomoki Misaka, Mitsuo Hara, Hirokazu Yano, Hidenori Okuzaki, Jun Matsui, Tsuyoshi Hasegawa, Takuya Matsumoto, Hirofumi Tanaka, Shusaku Nagano   +10 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Impact of community recruitment and inclusion initiatives on enrollment in the biomarker-driven MyTACTIC trial. [PDF]

Future Oncol
Zuniga RM, VanderWalde A, Schwartzberg LS, Spigel DR, Passler L, Hong J, Howland M, Darbonne WC, Szado T, Daniel D.   +9 more
europepmc   +1 more source

Regioisomeric Effects on Enhancing p‐Type Characteristics of Self‐Assembled Molecules in Inverted Perovskite Solar Cells

Advanced Science, EarlyView.
Regioisomeric effects are a critical design parameter in self‐assembled monolyaer (SAM) engineering, underscoring their importance for optimizing buried interface properties and advancing the performance and stability of inverted perovskite solar cells.
Myeong‐Ho Hong, Sanwan Liu, Seong Chan Cho, Seung‐Joo Chang, Sang Uck Lee, Nam‐Gyu Park   +5 more
wiley   +1 more source