Results 221 to 230 of about 17,696,681 (275)

A unified vision-language model for precision oncology and biomarker prediction in neuroblastoma. [PDF]

Nat Commun
Zhu J, Hu R, Yang S, Sun Q, Zhao Z, Cao J, Pan P, Wang K, Cui L, Tang H, Fang Q, Jiang S, Lei L, Zhang W, Xie J, Kang S, Xiao D, Xiao M, Zhai X, Jia Y, Chen J, Yuan W, Han X, Lu L, Zhao J, Wang X, Li Y, Xiang J, Zhu B.   +28 more
europepmc   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Conditional Perplexity Scoring for Large Language Model-Generated Differential Diagnoses in Case Reports: Preliminary Computational Evaluation. [PDF]

JMIR Form Res
Hirosawa T, Harada Y, Kawamura R, Shimizu T.   +3 more
europepmc   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Performance, Failures, and Oversight of a Large Language Model Agent for Clinical Data Analysis: Evaluation Study. [PDF]

J Med Internet Res
Wu Y, Fu DJ, Zhou Y, Wagner SK, Keane PA.   +4 more
europepmc   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

OmniExtract: an automatic data extraction tool based on large language model and prompt engineering. [PDF]

Brief Bioinform
Wang Y, Tang B, Wu S, Bei S, Gao X, Wu Y, Liu S, Hu H, Meng Y, Kong D, Zhao W.   +10 more
europepmc   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source